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CHICK:ITB1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ITGB1
Protein Name(s) Integrin beta-1

CSAT antigen JG22 antigen RGD-receptor

External Links
UniProt P07228
EMBL M14049
PIR A23947
UniGene Gga.111
ProteinModelPortal P07228
SMR P07228
IntAct P07228
MINT MINT-197077
STRING 9031.ENSGALP00000011559
PaxDb P07228
PRIDE P07228
eggNOG NOG287997
HOGENOM HOG000252936
HOVERGEN HBG006190
InParanoid P07228
PhylomeDB P07228
NextBio 20813580
PRO PR:P07228
Proteomes UP000000539
GO GO:0030054
GO:0008305
GO:0071438
GO:0030027
GO:0042470
GO:0005886
GO:0032587
GO:0046872
GO:0004872
GO:0007160
GO:0007229
GO:0007275
Gene3D 1.20.5.630
3.40.50.410
InterPro IPR013111
IPR027071
IPR015812
IPR014836
IPR002369
IPR012896
IPR016201
IPR002035
PANTHER PTHR10082
PTHR10082:SF28
Pfam PF07974
PF08725
PF07965
PF00362
PIRSF PIRSF002512
PRINTS PR01186
SMART SM00187
SM00423
SM00327
SUPFAM SSF103575
SSF53300
SSF69687
PROSITE PS00022
PS00243

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0009986

cell surface

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05556

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05556

C

Seeded From UniProt

complete

involved_in

GO:0033627

cell adhesion mediated by integrin

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05556

P

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

PMID:9548728[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000056)

Seeded From UniProt

complete

enables

GO:1990782

protein tyrosine kinase binding

PMID:17604018[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q00944-2
UniProtKB:Q92063

F

occurs_in:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:17604018[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0071438

invadopodium membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05556

C

Seeded From UniProt

complete

enables

GO:0098639

collagen binding involved in cell-matrix adhesion

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000008907
UniProtKB:P05556

F

Seeded From UniProt

complete

contributes_to

GO:0043236

laminin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96610
PANTHER:PTN000008907
RGD:2927

F

Seeded From UniProt

complete

involved_in

GO:0033627

cell adhesion mediated by integrin

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004657
MGI:MGI:96615
PANTHER:PTN000801545
UniProtKB:P05106
UniProtKB:P05556
UniProtKB:P18564

P

Seeded From UniProt

complete

contributes_to

GO:0019960

C-X3-C chemokine binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000008907
UniProtKB:P05556

F

Seeded From UniProt

complete

involved_in

GO:0016477

cell migration

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96610
PANTHER:PTN000801545

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96610
MGI:MGI:96611
MGI:MGI:96612
PANTHER:PTN000801545
RGD:1305581
RGD:2927
UniProtKB:M0RCF3
UniProtKB:P05106
UniProtKB:P05107
UniProtKB:P05556
UniProtKB:P16144
UniProtKB:P18084
UniProtKB:P26010
UniProtKB:P26012
WB:WBGene00003930

C

Seeded From UniProt

complete

part_of

GO:0008305

integrin complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004657
FB:FBgn0010395
MGI:MGI:96613
PANTHER:PTN000801545
RGD:2927
UniProtKB:M0RCF3
UniProtKB:P05106
WB:WBGene00003930
ZFIN:ZDB-GENE-071207-2

C

Seeded From UniProt

complete

involved_in

GO:0007229

integrin-mediated signaling pathway

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004657
MGI:MGI:96611
MGI:MGI:96614
PANTHER:PTN000801545
UniProtKB:P05107
UniProtKB:P05556
UniProtKB:P18084
UniProtKB:P26010
UniProtKB:P53714

P

Seeded From UniProt

complete

involved_in

GO:0007160

cell-matrix adhesion

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96610
MGI:MGI:96612
PANTHER:PTN000801545
UniProtKB:P05106
UniProtKB:P05107
UniProtKB:P05556
UniProtKB:P16144
UniProtKB:P18084
UniProtKB:P26010
UniProtKB:P26012

P

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004657
MGI:MGI:96614
PANTHER:PTN000801545
RGD:2927
UniProtKB:M0RCF3
UniProtKB:P05106
UniProtKB:P05556
UniProtKB:P07228
UniProtKB:P18564

C

Seeded From UniProt

complete

enables

GO:0005178

integrin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96610
MGI:MGI:96612
MGI:MGI:96614
MGI:MGI:96615
PANTHER:PTN000801545
RGD:2927
UniProtKB:P05106

F

Seeded From UniProt

complete

enables

GO:0001968

fibronectin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000008907
RGD:2927
UniProtKB:P05556

F

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027071

P

Seeded From UniProt

complete

involved_in

GO:0007160

cell-matrix adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027071

P

Seeded From UniProt

complete

involved_in

GO:0007229

integrin-mediated signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027071

P

Seeded From UniProt

complete

part_of

GO:0008305

integrin complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027071

C

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027071

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-NUL-2467431

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007229

integrin-mediated signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0401

P

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0001726

ruffle

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0300

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0310

C

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0291

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0118

C

Seeded From UniProt

complete

part_of

GO:0042470

melanosome

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0161

C

Seeded From UniProt

complete

part_of

GO:0032587

ruffle membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0301

C

Seeded From UniProt

complete

part_of

GO:0071438

invadopodium membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0290

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Huttenlocher, A et al. (1998) Integrin and cadherin synergy regulates contact inhibition of migration and motile activity. J. Cell Biol. 141 515-26 PubMed GONUTS page
  2. 2.0 2.1 Jin, EJ et al. (2007) MMP-2 functions as a negative regulator of chondrogenic cell condensation via down-regulation of the FAK-integrin beta1 interaction. Dev. Biol. 308 474-84 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page