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CHICK:INHBA

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) INHBA
Protein Name(s) Inhibin beta A chain

Activin beta-A chain

External Links
UniProt P27092
EMBL U26946
U42377
M61167
M57407
PIR B36193
RefSeq NP_990727.1
UniGene Gga.3982
ProteinModelPortal P27092
SMR P27092
STRING 9031.ENSGALP00000036647
PaxDb P27092
PRIDE P27092
GeneID 396361
KEGG gga:396361
CTD 3624
eggNOG NOG312557
HOGENOM HOG000220890
HOVERGEN HBG105613
InParanoid P27092
KO K04667
PhylomeDB P27092
NextBio 20816406
PRO PR:P27092
Proteomes UP000000539
GO GO:0043509
GO:0005576
GO:0043512
GO:0005125
GO:0032924
GO:0007050
GO:0000082
GO:0040007
GO:0002244
GO:0042541
GO:0008584
GO:0007498
GO:0045786
GO:0030308
GO:0008285
GO:0001541
GO:0060021
GO:0045648
GO:2001241
GO:0045944
GO:0042701
GO:0046880
GO:0006357
GO:0042493
Gene3D 2.10.90.10
InterPro IPR029034
IPR000491
IPR001839
IPR001111
IPR015615
PANTHER PTHR11848
Pfam PF00019
PF00688
PRINTS PR00670
SMART SM00204
SUPFAM SSF57501
PROSITE PS51362

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0032924

activin receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:2001241

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0060021

roof of mouth development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0046880

regulation of follicle-stimulating hormone secretion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0045786

negative regulation of cell cycle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0045648

positive regulation of erythrocyte differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

part_of

GO:0043512

inhibin A complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

C

Seeded From UniProt

complete

part_of

GO:0043509

activin A complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

C

Seeded From UniProt

complete

involved_in

GO:0042701

progesterone secretion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0042541

hemoglobin biosynthetic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0042493

response to drug

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0030308

negative regulation of cell growth

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0008584

male gonad development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0007498

mesoderm development

PMID:9694626[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007050

cell cycle arrest

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

C

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

F

Seeded From UniProt

complete

involved_in

GO:0002244

hematopoietic progenitor cell differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0001541

ovarian follicle development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0000082

G1/S transition of mitotic cell cycle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08476

P

Seeded From UniProt

complete

involved_in

GO:0060395

SMAD protein signal transduction

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1338027
MGI:MGI:88180
MGI:MGI:88182
MGI:MGI:95689
MGI:MGI:97359
PANTHER:PTN000218063
UniProtKB:O95390
UniProtKB:P12643
UniProtKB:P12644
UniProtKB:P18075
UniProtKB:P22004
UniProtKB:P43026
UniProtKB:P61812
UniProtKB:Q6KF10
UniProtKB:Q99988

P

Seeded From UniProt

complete

involved_in

GO:0048468

cell development

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103302
PANTHER:PTN000218063

P

Seeded From UniProt

complete

involved_in

GO:0043408

regulation of MAPK cascade

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107335
PANTHER:PTN000218063

P

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98726
PANTHER:PTN000218063

P

Seeded From UniProt

complete

involved_in

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107335
MGI:MGI:1338820
MGI:MGI:88182
MGI:MGI:95684
MGI:MGI:98727
PANTHER:PTN000218063
UniProtKB:O95393
UniProtKB:P01137
UniProtKB:P08476
UniProtKB:P12643
UniProtKB:P12644
UniProtKB:P18075
UniProtKB:P22003
UniProtKB:P22004
UniProtKB:Q6KF10
UniProtKB:Q7Z4P5
UniProtKB:Q96S42
UniProtKB:Q9UK05

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000490
MGI:MGI:103302
MGI:MGI:1338027
MGI:MGI:88177
MGI:MGI:88180
MGI:MGI:95691
MGI:MGI:98725
MGI:MGI:98726
PANTHER:PTN000218063
RGD:1305979
RGD:2211
RGD:2212
RGD:2213
RGD:2214
RGD:2912
RGD:2913
RGD:3115
RGD:3851
RGD:62074
RGD:620743
RGD:621512
RGD:69051
RGD:70491
UniProtKB:O14793
UniProtKB:O42220
UniProtKB:O95393
UniProtKB:P01137
UniProtKB:P12643
UniProtKB:P12644
UniProtKB:P18075
UniProtKB:P30371
UniProtKB:P61812
UniProtKB:Q96S42
UniProtKB:Q99988
WB:WBGene00000903

C

Seeded From UniProt

complete

enables

GO:0005160

transforming growth factor beta receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98725
PANTHER:PTN000218063
UniProtKB:P61812

F

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000218063
UniProtKB:P08476
UniProtKB:P12644

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000491

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000491

C

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001839

F

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Levin, M (1998) The roles of activin and follistatin signaling in chick gastrulation. Int. J. Dev. Biol. 42 553-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page