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CHICK:GON1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) GNRH1
Protein Name(s) Progonadoliberin-1

Progonadoliberin I Gonadoliberin-1 Gonadoliberin I Gonadotropin-releasing hormone I GnRH-I Luliberin I Luteinizing hormone-releasing hormone I LH-RH I GnRH-associated peptide 1 GnRH-associated peptide I

External Links
UniProt P37042
EMBL X69491
PIR I50644
RefSeq NP_001074346.1
UniGene Gga.41802
STRING 9031.ENSGALP00000000365
Ensembl ENSGALT00000000366
GeneID 770134
KEGG gga:770134
CTD 2796
eggNOG NOG39107
GeneTree ENSGT00390000008225
HOGENOM HOG000033698
HOVERGEN HBG014746
InParanoid P37042
KO K05252
OMA SGQHWSY
OrthoDB EOG7JX36N
PhylomeDB P37042
TreeFam TF330934
Reactome REACT_284991
REACT_310663
NextBio 20920357
PRO PR:P37042
Proteomes UP000000539
ExpressionAtlas P37042
GO GO:0005623
GO:0005576
GO:0005183
GO:0031530
GO:0032275
GO:0007275
GO:2001223
GO:0033686
GO:0010468
GO:0046885
GO:2000354
GO:2000843
GO:0000003
GO:0045471
GO:0048545
InterPro IPR002012
IPR019792
IPR004079
PANTHER PTHR10522
PRINTS PR01541
PROSITE PS00473

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0030424

axon

PMID:3277716[1]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0006134)
  • part_of:(UBERON:0002197)
  • part_of:(UBERON:0002622)
  • part_of:(UBERON:0001930)
  • part_of:(UBERON:0001932)
  • part_of:(UBERON:0002746)
  • part_of:(UBERON:0001935)

Seeded From UniProt

complete

involved_in

GO:1904014

response to serotonin

PMID:3277716[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(GO:0043204)

Seeded From UniProt

complete

involved_in

GO:0043279

response to alkaloid

PMID:3277716[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(GO:0043204)

Seeded From UniProt

complete

part_of

GO:0043204

perikaryon

PMID:3277716[1]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0001928)
  • part_of:(UBERON:0000446)
  • part_of:(UBERON:0002622)
  • part_of:(UBERON:0001930)
  • part_of:(UBERON:0001877)
  • part_of:(UBERON:0002219)
  • part_of:(UBERON:0001643)

Seeded From UniProt

complete

involved_in

GO:0032275

luteinizing hormone secretion

PMID:3282021[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000843

regulation of testosterone secretion

PMID:1564423[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0033686

positive regulation of luteinizing hormone secretion

PMID:1564423[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0033686

positive regulation of luteinizing hormone secretion

PMID:7772235[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0031530

gonadotropin-releasing hormone receptor binding

PMID:11112780[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000003

reproduction

PMID:2179458[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

PMID:7050119[7]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:7050119[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005183

gonadotropin hormone-releasing hormone activity

PMID:7050119[7]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0031530

gonadotropin-releasing hormone receptor binding

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001315053
UniProtKB:P37042

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001315053
RGD:2720

C

Seeded From UniProt

complete

enables

GO:0005183

gonadotropin hormone-releasing hormone activity

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001315053
RGD:2720
UniProtKB:P37042

F

Seeded From UniProt

complete

involved_in

GO:0000003

reproduction

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001315053
UniProtKB:P37042

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005183

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005183

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005183

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:2001223

negative regulation of neuron migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P13562
ensembl:ENSMUSP00000106724

P

Seeded From UniProt

complete

involved_in

GO:2000354

regulation of ovarian follicle development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P13562
ensembl:ENSMUSP00000106724

P

Seeded From UniProt

complete

involved_in

GO:0048545

response to steroid hormone

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P13562
ensembl:ENSMUSP00000106724

P

Seeded From UniProt

complete

involved_in

GO:0045471

response to ethanol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P13562
ensembl:ENSMUSP00000106724

P

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P13562
ensembl:ENSMUSP00000106724

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P13562
ensembl:ENSMUSP00000106724

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002012

F

Seeded From UniProt

complete

enables

GO:0005183

gonadotropin hormone-releasing hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004079

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002012

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002012

P

Seeded From UniProt

complete

involved_in

GO:0046885

regulation of hormone biosynthetic process

PMID:7772235[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 Mikami, S et al. (1988) Localization of avian LHRH-immunoreactive neurons in the hypothalamus of the domestic fowl, Gallus domesticus, and the Japanese quail, Coturnix coturnix. Cell Tissue Res. 251 51-8 PubMed GONUTS page
  2. ↑ King, JA et al. (1988) Interaction of endogenous chicken gonadotrophin-releasing hormone-I and -II on chicken pituitary cells. J. Endocrinol. 117 43-9 PubMed GONUTS page
  3. ↑ 3.0 3.1 Guémené, D & Williams, JB (1992) In-vitro and in-vivo responses to chicken LHRH-I and chicken LHRH-II in male turkeys (Meleagris gallopavo). J. Endocrinol. 132 387-93 PubMed GONUTS page
  4. ↑ 4.0 4.1 You, S et al. (1995) Sequence analysis of the turkey LH beta subunit and its regulation by gonadotrophin-releasing hormone and prolactin in cultured pituitary cells. J. Mol. Endocrinol. 14 117-29 PubMed GONUTS page
  5. ↑ Sun, YM et al. (2001) A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants. J. Biol. Chem. 276 7754-61 PubMed GONUTS page
  6. ↑ Sharp, PJ et al. (1990) Physiological roles of chicken LHRH-I and -II in the control of gonadotrophin release in the domestic chicken. J. Endocrinol. 124 291-9 PubMed GONUTS page
  7. ↑ 7.0 7.1 7.2 King, JA & Millar, RP (1982) Structure of chicken hypothalamic luteinizing hormone-releasing hormone. II. Isolation and characterization. J. Biol. Chem. 257 10729-32 PubMed GONUTS page
  8. ↑ 8.0 8.1 8.2 8.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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