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CHICK:DPOG1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) POLG (synonyms: POLG1)
Protein Name(s) DNA polymerase subunit gamma-1

Mitochondrial DNA polymerase catalytic subunit

External Links
UniProt Q92076
EMBL U60297
UniGene Gga.2135
ProteinModelPortal Q92076
STRING 9031.ENSGALP00000037807
PaxDb Q92076
eggNOG COG0749
HOGENOM HOG000176668
HOVERGEN HBG051400
InParanoid Q92076
PhylomeDB Q92076
Proteomes UP000000539
GO GO:0005760
GO:0042645
GO:0003682
GO:0003677
GO:0003887
GO:0006260
GO:0000731
GO:0006298
InterPro IPR019760
IPR002297
IPR001098
PANTHER PTHR10267
Pfam PF00476
PRINTS PR00867
SMART SM00482
PROSITE PS00447

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006298

mismatch repair

PMID:3941068[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006261

DNA-dependent DNA replication

PMID:3930505[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

PMID:3930505[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006298

mismatch repair

PMID:3930505[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000731

DNA synthesis involved in DNA repair

PMID:3930505[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0042645

mitochondrial nucleoid

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P54098

C

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P54098

F

Seeded From UniProt

complete

enables

GO:0008408

3'-5' exonuclease activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000030201
SGD:S000005857

F

Seeded From UniProt

complete

involved_in

GO:0006264

mitochondrial DNA replication

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004406
MGI:MGI:1196389
PANTHER:PTN000030201
PomBase:SPCC24B10.22
SGD:S000005857
WB:WBGene00013258

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000030201
PomBase:SPCC24B10.22
RGD:620057
SGD:S000005857

C

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004406
PANTHER:PTN000030201
RGD:620057
SGD:S000005857
UniProtKB:P54098
UniProtKB:Q92076

F

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008408

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001098
InterPro:IPR002297

F

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001098
InterPro:IPR019760

F

Seeded From UniProt

complete

part_of

GO:0005760

gamma DNA polymerase complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002297

C

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001098
InterPro:IPR002297
InterPro:IPR019760

P

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.7

F

Seeded From UniProt

complete

part_of

GO:0042645

mitochondrial nucleoid

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1135
UniProtKB-SubCell:SL-0269

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0239

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496
UniProtKB-SubCell:SL-0173

C

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kunkel, TA & Alexander, PS (1986) The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation. J. Biol. Chem. 261 160-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Kunkel, TA (1985) The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis. J. Biol. Chem. 260 12866-74 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page