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CHICK:DNM3A

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) DNMT3A
Protein Name(s) DNA (cytosine-5)-methyltransferase 3A

Dnmt3a

External Links
UniProt Q4W5Z4
EMBL AB214886
RefSeq NP_001020003.1
UniGene Gga.6002
ProteinModelPortal Q4W5Z4
SMR Q4W5Z4
STRING 9031.ENSGALP00000006352
REBASE 11753
PaxDb Q4W5Z4
GeneID 421991
KEGG gga:421991
CTD 1788
eggNOG NOG70699
HOVERGEN HBG051381
InParanoid Q4W5Z4
KO K17398
PhylomeDB Q4W5Z4
NextBio 20824684
PRO PR:Q4W5Z4
Proteomes UP000000539
GO GO:0005737
GO:0000791
GO:0016363
GO:0005634
GO:0003886
GO:0003677
GO:0046872
GO:0090116
GO:0016568
GO:0006306
GO:0006355
GO:0006351
Gene3D 3.40.50.150
InterPro IPR025766
IPR018117
IPR001525
IPR030487
IPR000313
IPR029063
PANTHER PTHR23068:SF10
Pfam PF00855
SMART SM00293
SUPFAM SSF53335
PROSITE PS51533
PS00094
PS50812
PS51679

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0001046

core promoter sequence-specific DNA binding

PMID:19046370[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(UBERON:0001928)

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:19046370[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0001928)

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:25159139[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0010328)

Seeded From UniProt

complete

involved_in

GO:0071774

response to fibroblast growth factor

PMID:25159139[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0010328)

Seeded From UniProt

complete

part_of

GO:0016363

nuclear matrix

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

C

Seeded From UniProt

complete

involved_in

GO:0006306

DNA methylation

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

C

Seeded From UniProt

complete

enables

GO:0003886

DNA (cytosine-5-)-methyltransferase activity

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

F

Seeded From UniProt

complete

part_of

GO:0000791

euchromatin

PMID:12138111[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6K1

C

Seeded From UniProt

complete

involved_in

GO:0090116

C-5 methylation of cytosine

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003886

P

Seeded From UniProt

complete

involved_in

GO:0090116

C-5 methylation of cytosine

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003886

P

Seeded From UniProt

complete

involved_in

GO:0006306

DNA methylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030487

P

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001525

F

Seeded From UniProt

complete

enables

GO:0009008

DNA-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030487

F

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030487

P

Seeded From UniProt

complete

enables

GO:0003886

DNA (cytosine-5-)-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.37

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Yossifoff, M et al. (2008) Dynamic changes in DNA methylation during thermal control establishment affect CREB binding to the brain-derived neurotrophic factor promoter. Eur. J. Neurosci. 28 2267-77 PubMed GONUTS page
  2. 2.0 2.1 Kumar, D & Lassar, AB (2014) Fibroblast growth factor maintains chondrogenic potential of limb bud mesenchymal cells by modulating DNMT3A recruitment. Cell Rep 8 1419-31 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Chen, T et al. (2002) A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. J. Biol. Chem. 277 38746-54 PubMed GONUTS page