CHICK:CD28

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	CD28
Protein Name(s)	T-cell-specific surface glycoprotein CD28 homolog CHT28
External Links
UniProt	P31043
EMBL	X67915
PIR	I50619
RefSeq	NP_990642.1
UniGene	Gga.723
ProteinModelPortal	P31043
SMR	P31043
STRING	9031.ENSGALP00000014099
PaxDb	P31043
Ensembl	ENSGALT00000014115
GeneID	396249
KEGG	gga:396249
CTD	940
eggNOG	NOG48152
GeneTree	ENSGT00530000063873
HOGENOM	HOG000276892
HOVERGEN	HBG004094
InParanoid	P31043
KO	K06470
OMA	VNGNYSH
OrthoDB	EOG7W6WMJ
PhylomeDB	P31043
TreeFam	TF335679
Reactome	REACT_278228 REACT_284939 REACT_285183 REACT_329277
NextBio	20816301
PRO	PR:P31043
Proteomes	UP000000539
GO	GO:0009897 GO:0001772 GO:0044214 GO:0097190 GO:0006955 GO:0045060 GO:0046641 GO:0002863 GO:0048304 GO:0014068 GO:0051897 GO:0045944 GO:0045066 GO:0031295 GO:0050852
Gene3D	2.60.40.10
InterPro	IPR008093 IPR013783 IPR003599
PRINTS	PR01717
SMART	SM00409

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0044214	spanning component of plasma membrane	PMID:19013189^[1]	ECO:0000250	sequence similarity evidence used in manual assertion		C	Seeded From UniProt	Missing: with/from
part_of	GO:0098636	protein complex involved in cell adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	C	Seeded From UniProt	complete
involved_in	GO:0045840	positive regulation of mitotic nuclear division	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0045086	positive regulation of interleukin-2 biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0045066	regulatory T cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0042110	T cell activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0042102	positive regulation of T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0032753	positive regulation of interleukin-4 production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0032733	positive regulation of interleukin-10 production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	P	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	C	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	C	Seeded From UniProt	complete
enables	GO:0005070	SH3/SH2 adaptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	F	Seeded From UniProt	complete
enables	GO:0002020	protease binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P10747 ensembl:ENSP00000324890	F	Seeded From UniProt	complete
involved_in	GO:0097190	apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0051897	positive regulation of protein kinase B signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0050852	T cell receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0048304	positive regulation of isotype switching to IgG isotypes	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0046641	positive regulation of alpha-beta T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0045589	regulation of regulatory T cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0045086	positive regulation of interleukin-2 biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0045060	negative thymic T cell selection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0042102	positive regulation of T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
involved_in	GO:0031295	T cell costimulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	F	Seeded From UniProt	complete
involved_in	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	C	Seeded From UniProt	complete
involved_in	GO:0002863	positive regulation of inflammatory response to antigenic stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	P	Seeded From UniProt	complete
part_of	GO:0001772	immunological synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31041 ensembl:ENSMUSP00000027165	C	Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008093	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008093	C	Seeded From UniProt	complete
involved_in	GO:0042129	regulation of T cell proliferation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR040216	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Powell, F et al. (2009) Development of reagents to study the turkey's immune response: Identification and molecular cloning of turkey CD4, CD8alpha and CD28. Dev. Comp. Immunol. 33 540-6 PubMed GONUTS page

[PMID:19013189-1] Powell, F et al. (2009) Development of reagents to study the turkey's immune response: Identification and molecular cloning of turkey CD4, CD8alpha and CD28. Dev. Comp. Immunol. 33 540-6 PubMed GONUTS page

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CHICK:CD28

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