CHICK:CCNA2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	CCNA2 (synonyms: CCNA, CYCA)
Protein Name(s)	Cyclin-A2 Cyclin-A
External Links
UniProt	P43449
EMBL	X72892
PIR	S38812
RefSeq	NP_990575.1
UniGene	Gga.4129
ProteinModelPortal	P43449
SMR	P43449
PaxDb	P43449
GeneID	396172
KEGG	gga:396172
CTD	890
eggNOG	COG5024
HOGENOM	HOG000167672
HOVERGEN	HBG106244
InParanoid	P43449
KO	K06627
PhylomeDB	P43449
NextBio	20816226
PRO	PR:P43449
Proteomes	UP000000539
GO	GO:0005634 GO:0051301 GO:0007067 GO:0000079 GO:0010389
Gene3D	1.10.472.10
InterPro	IPR013763 IPR015453 IPR004367 IPR006671
PANTHER	PTHR10177:SF69
Pfam	PF02984 PF00134
SMART	SM00385
SUPFAM	SSF47954
PROSITE	PS00292

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005654	nucleoplasm	PMID:8282760^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	PMID:8282760^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20248	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20248	C	Seeded From UniProt	complete
part_of	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20248	C	Seeded From UniProt	complete
involved_in	GO:0044843	cell cycle G1/S phase transition	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20248	P	Seeded From UniProt	complete
involved_in	GO:0000086	G2/M transition of mitotic cell cycle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20248	P	Seeded From UniProt	complete
part_of	GO:0097124	cyclin A2-CDK2 complex	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108069 PANTHER:PTN000020428 UniProtKB:P20248	C	Seeded From UniProt	complete
involved_in	GO:0045787	positive regulation of cell cycle	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88302 PANTHER:PTN000019791	P	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108069 MGI:MGI:88313 MGI:MGI:88315 MGI:MGI:88316 PANTHER:PTN000019791 RGD:1307783 RGD:2291 RGD:2293 RGD:2294 RGD:621083 RGD:68384 UniProtKB:P14635 UniProtKB:P20248 UniProtKB:P24385 UniProtKB:P30279 UniProtKB:P30281	F	Seeded From UniProt	complete
enables	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000175354 FB:FBgn0000404 FB:FBgn0000405 FB:FBgn0010315 FB:FBgn0010317 FB:FBgn0010382 MGI:MGI:1329034 MGI:MGI:88313 MGI:MGI:88316 PANTHER:PTN000019791 PomBase:SPBC19F5.01c SGD:S000000038 SGD:S000002314 SGD:S000003340 SGD:S000003341 SGD:S000004200 SGD:S000004812 SGD:S000006177 SGD:S000006323 SGD:S000006324 WB:WBGene00000865 WB:WBGene00000868 WB:WBGene00000871	F	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000019791 RGD:2293 RGD:621083 RGD:68384 UniProtKB:P30279 WB:WBGene00000871	P	Seeded From UniProt	complete
involved_in	GO:0007088	regulation of mitotic nuclear division	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000404 PANTHER:PTN000019791 WB:WBGene00000871	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000404 MGI:MGI:108069 MGI:MGI:2145534 MGI:MGI:88302 MGI:MGI:88313 MGI:MGI:88314 MGI:MGI:88315 PANTHER:PTN000019791 PomBase:SPBC582.03 RGD:2291 RGD:2294 RGD:68384 SGD:S000002314 SGD:S000003340 SGD:S000004200 SGD:S000004812 SGD:S000006177 SGD:S000006323 TAIR:locus:2031407 TAIR:locus:2142504 TAIR:locus:2160722 TAIR:locus:2205871 UniProtKB:P14635 UniProtKB:P20248 UniProtKB:P22674 UniProtKB:Q9C6A9 WB:WBGene00000865 WB:WBGene00000868	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000404 FB:FBgn0000405 FB:FBgn0010382 FB:FBgn0015625 MGI:MGI:108069 MGI:MGI:88302 MGI:MGI:88313 MGI:MGI:88314 MGI:MGI:88315 MGI:MGI:88316 PANTHER:PTN000019791 PomBase:SPBC582.03 RGD:2291 RGD:2294 RGD:2295 RGD:621059 RGD:68384 SGD:S000000038 SGD:S000002314 SGD:S000003340 SGD:S000004200 SGD:S000004812 SGD:S000006177 SGD:S000006323 SGD:S000006324 TAIR:locus:2031407 TAIR:locus:2034250 TAIR:locus:2120081 TAIR:locus:2124331 TAIR:locus:2142504 TAIR:locus:2196563 TAIR:locus:2205871 UniProtKB:P14635 UniProtKB:P20248 UniProtKB:P24385 UniProtKB:P24864 UniProtKB:P30279 UniProtKB:P41002 UniProtKB:Q9C6A9 WB:WBGene00000865 WB:WBGene00000868 WB:WBGene00000871	C	Seeded From UniProt	complete
contributes_to	GO:0004672	protein kinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88313 PANTHER:PTN000019791	F	Seeded From UniProt	complete
part_of	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88313 MGI:MGI:88316 PANTHER:PTN000019791 PomBase:SPAPB2B4.03 SGD:S000003340 SGD:S000006177 UniProtKB:P20248 UniProtKB:P24385 UniProtKB:P30279 UniProtKB:P30281 UniProtKB:P43449	C	Seeded From UniProt	complete
involved_in	GO:0000278	mitotic cell cycle	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000404 FB:FBgn0010317 FB:FBgn0015625 PANTHER:PTN000019791 RGD:2291 UniProtKB:P22674 WB:WBGene00000865 WB:WBGene00000868	P	Seeded From UniProt	complete
involved_in	GO:0000086	G2/M transition of mitotic cell cycle	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000020428 UniProtKB:P20248	P	Seeded From UniProt	complete
involved_in	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000175354 CGD:CAL0000185532 PANTHER:PTN000019791 SGD:S000000038 SGD:S000002314 SGD:S000003340 SGD:S000003341 SGD:S000004200 SGD:S000004812 SGD:S000006177 SGD:S000006323 SGD:S000006324 UniProtKB:Q59YH3	P	Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004672	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004367	C	Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Maridor, G et al. (1993) Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. J. Cell. Sci. 106 ( Pt 2) 535-44 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:8282760-1] 1.0 ^1.1 Maridor, G et al. (1993) Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. J. Cell. Sci. 106 ( Pt 2) 535-44 PubMed GONUTS page

[PMID:21873635-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:CCNA2

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