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CHICK:CATD

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CTSD
Protein Name(s) Cathepsin D

Cathepsin D light chain Cathepsin D heavy chain

External Links
UniProt Q05744
EMBL S49650
PIR I51185
RefSeq NP_990508.1
UniGene Gga.1094
ProteinModelPortal Q05744
SMR Q05744
STRING 9031.ENSGALP00000010662
MEROPS A01.009
PaxDb Q05744
PRIDE Q05744
Ensembl ENSGALT00000010676
GeneID 396090
KEGG gga:396090
CTD 1509
eggNOG NOG248684
GeneTree ENSGT00760000118929
HOGENOM HOG000197681
HOVERGEN HBG000482
InParanoid Q05744
KO K01379
OMA PFYAMYE
OrthoDB EOG7HQN88
PhylomeDB Q05744
TreeFam TF314990
Reactome REACT_336937
REACT_349136
NextBio 20816148
PRO PR:Q05744
Proteomes UP000000539
ExpressionAtlas Q05744
GO GO:0005615
GO:0005764
GO:0005739
GO:0004190
GO:0000045
GO:0006914
GO:0030163
GO:0006508
Gene3D 2.40.70.10
InterPro IPR001461
IPR001969
IPR012848
IPR021109
PANTHER PTHR13683
Pfam PF07966
PF00026
PRINTS PR00792
SUPFAM SSF50630
PROSITE PS00141

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0008219

cell death

PMID:16987511[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0012501

programmed cell death

PMID:16987511[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

PMID:16987511[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030163

protein catabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000201569
PANTHER:PTN000342793
UniProtKB:P0CY27
UniProtKB:Q5A8N2
UniProtKB:Q5AC08

P

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000190503
CGD:CAL0000194661
CGD:CAL0000196689
CGD:CAL0000201140
MGI:MGI:1346542
PANTHER:PTN000342793
RGD:621511
SGD:S000002551
TAIR:locus:2008940
UniProtKB:P00797
UniProtKB:P0CY27
UniProtKB:P41748
UniProtKB:P43094
UniProtKB:P56817
UniProtKB:Q59VH7
UniProtKB:Q5AC08
UniProtKB:Q8I6Z5
WB:WBGene00000217

P

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88562
PANTHER:PTN002671460
RGD:621511
UniProtKB:P07339
UniProtKB:Q05744

C

Seeded From UniProt

complete

enables

GO:0004190

aspartic-type endopeptidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000196689
MGI:MGI:107361
MGI:MGI:1915935
MGI:MGI:88562
PANTHER:PTN000342793
PomBase:SPCC1795.09
RGD:2446
SGD:S000001277
SGD:S000002551
SGD:S000004110
SGD:S000004111
TAIR:locus:2145954
UniProtKB:P00797
UniProtKB:P0CY27
UniProtKB:P14091
UniProtKB:P20142
UniProtKB:P56817
UniProtKB:Q4WNV0
UniProtKB:Q5AC08
UniProtKB:Q8I6Z5
UniProtKB:Q9LTW4
UniProtKB:Q9Y5Z0

F

Seeded From UniProt

complete

enables

GO:0004190

aspartic-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001461
InterPro:IPR001969
InterPro:IPR033144

F

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033144

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001461
InterPro:IPR001969
InterPro:IPR033144

P

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0458
UniProtKB-SubCell:SL-0158

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0004190

aspartic-type endopeptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0064

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Zuzarte-Luis, V et al. (2007) Lysosomal cathepsins in embryonic programmed cell death. Dev. Biol. 301 205-17 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page