CHICK:AGRIN

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	AGRN (synonyms: AGRIN)
Protein Name(s)	Agrin Agrin N-terminal 110 kDa subunit Agrin C-terminal 110 kDa subunit Agrin C-terminal 90 kDa fragment C90 Agrin C-terminal 22 kDa fragment C22
External Links
UniProt	P31696
EMBL	U35613 M94271 M97371 M97372 U07271
PIR	JH0591
UniGene	Gga.4448 Gga.48948
PDB	1JB3 1JC7 1PXU 1PZ7 1PZ8 1PZ9 1Q56 3I70
PDBsum	1JB3 1JC7 1PXU 1PZ7 1PZ8 1PZ9 1Q56 3I70
ProteinModelPortal	P31696
BioGrid	676782
IntAct	P31696
STRING	9031.ENSGALP00000039379
PaxDb	P31696
PRIDE	P31696
eggNOG	NOG312635
HOGENOM	HOG000033860
HOVERGEN	HBG080471
InParanoid	P31696
Reactome	REACT_343968
EvolutionaryTrace	P31696
NextBio	20816574
PRO	PR:P31696
Proteomes	UP000000539
GO	GO:0005605 GO:0030054 GO:0005576 GO:0016021 GO:0005886 GO:0045202 GO:0030548 GO:0005509 GO:0035374 GO:0002162 GO:0043395 GO:0008201 GO:0043236 GO:0033691 GO:0030297 GO:0007171 GO:0030154 GO:0007213 GO:0007275 GO:0051491 GO:0043547 GO:0045887 GO:0045944 GO:0043113 GO:0010469
Gene3D	2.60.120.200 3.30.70.960
InterPro	IPR004850 IPR013320 IPR000742 IPR013032 IPR000152 IPR002049 IPR003645 IPR002350 IPR001791 IPR000082 IPR008993
Pfam	PF00008 PF00050 PF07648 PF00053 PF00054 PF03146 PF01390
SMART	SM00181 SM00180 SM00274 SM00280 SM00282 SM00200
SUPFAM	SSF49899 SSF50242 SSF82671
PROSITE	PS00010 PS00022 PS01186 PS50026 PS01248 PS50027 PS51465 PS50025 PS51121 PS50024

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043236	laminin binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_at:(CL:0002372)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
involved_in	GO:0043113	receptor clustering	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00468	P		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00468	C		Seeded From UniProt	complete
involved_in	GO:0051491	positive regulation of filopodium assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25304	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25304	P		Seeded From UniProt	complete
involved_in	GO:0045887	positive regulation of synaptic growth at neuromuscular junction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2ASQ1	P		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06687	C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25304	C		Seeded From UniProt	complete
enables	GO:0043395	heparan sulfate proteoglycan binding	PMID:17649979^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043236	laminin binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0043113	receptor clustering	PMID:8607994^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0035374	chondroitin sulfate binding	PMID:12773545^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0033691	sialic acid binding	PMID:17649979^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25304	P		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8607994^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	PMID:17012237^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0008201	heparin binding	PMID:8607994^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	PMID:17649979^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:8607994^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:10594644^[9]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0098965	extracellular matrix of synaptic cleft	PMID:10594644^[9]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0000061) part_of:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0098965	extracellular matrix of synaptic cleft	PMID:10594644^[9]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(GO:0098684) part_of:(UBERON:0000061)	Seeded From UniProt	complete
part_of	GO:0098684	photoreceptor ribbon synapse	PMID:10594644^[9]	ECO:0006003	electron microscopy evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030297	P		Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001881	F		Seeded From UniProt	complete
involved_in	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004850	P		Seeded From UniProt	complete
involved_in	GO:0043113	receptor clustering	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004850	P		Seeded From UniProt	complete
enables	GO:0043236	laminin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004850	F		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_at:(CL:0002372)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_at:(CL:0002372)	Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_at:(CL:0002372)	Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
part_of	GO:0045178	basal part of cell	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:8522611^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002372)	Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_at:(CL:0002372)	Seeded From UniProt	complete
enables	GO:0043237	laminin-1 binding	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:9151673^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9151673^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001797)	Seeded From UniProt	complete
enables	GO:0002162	dystroglycan binding	PMID:9151673^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A1D5PFK3 UniProtKB:A4VAR9	F	occurs_in:(UBERON:0001134)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005539	glycosaminoglycan binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0050840	extracellular matrix binding	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0030548	acetylcholine receptor regulator activity	PMID:8522611^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0071340	C		Seeded From UniProt	complete
involved_in	GO:0099601	regulation of neurotransmitter receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030548	P		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	PMID:16364653^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046847	filopodium assembly	PMID:19139104^[11]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0043005) part_of:(CL:0000740)	Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:19139104^[11]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000740) part_of:(GO:0043005)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:19139104^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:19139104^[11]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(GO:0043005) part_of:(CL:0000740)	Seeded From UniProt	complete
involved_in	GO:0046847	filopodium assembly	PMID:16364653^[10]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0011103)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:16364653^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(GO:0009986) part_of:(CL:0000740)	Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(GO:0030424) occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001793) part_of:(GO:0005615)\|part_of:(UBERON:0001797) part_of:(GO:0005615)	Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:7852425^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:7852425^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:9184982^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000966)\|part_of:(UBERON:0001981)\|part_of:(CL:0002573)	Seeded From UniProt	complete
part_of	GO:0031012	extracellular matrix	PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007528	neuromuscular junction development	PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007158	neuron cell-cell adhesion	PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4] PMID:7852425^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-NUL-2467092 Reactome:R-GGA-2467642 Reactome:R-GGA-2467578	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770 UniProtKB-SubCell:SL-0258	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
involved_in	GO:0031532	actin cytoskeleton reorganization	PMID:19139104^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	PMID:19139104^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 ^1.15 ^1.16 ^1.17 ^1.18 ^1.19 ^1.20 ^1.21 ^1.22 ^1.23 ^1.24 ^1.25 ^1.26 ^1.27 ^1.28 ^1.29 Halfter, W et al. (1997) Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways. J. Comp. Neurol. 383 1-17 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 ^2.19 ^2.20 ^2.21 ^2.22 ^2.23 ^2.24 ^2.25 ^2.26 ^2.27 ^2.28 ^2.29 ^2.30 ^2.31 ^2.32 ^2.33 ^2.34 ^2.35 ^2.36 ^2.37 ^2.38 ^2.39 ^2.40 ^2.41 ^2.42 Denzer, AJ et al. (1997) Agrin binds to the nerve-muscle basal lamina via laminin. J. Cell Biol. 137 671-83 PubMed GONUTS page
↑ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 ^3.21 ^3.22 ^3.23 ^3.24 ^3.25 ^3.26 ^3.27 ^3.28 ^3.29 ^3.30 ^3.31 ^3.32 ^3.33 ^3.34 ^3.35 ^3.36 ^3.37 ^3.38 ^3.39 ^3.40 ^3.41 ^3.42 ^3.43 ^3.44 ^3.45 ^3.46 ^3.47 ^3.48 ^3.49 Denzer, AJ et al. (1995) An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. J. Cell Biol. 131 1547-60 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 ^4.15 ^4.16 ^4.17 ^4.18 ^4.19 ^4.20 ^4.21 ^4.22 ^4.23 ^4.24 ^4.25 ^4.26 ^4.27 ^4.28 ^4.29 ^4.30 ^4.31 ^4.32 ^4.33 ^4.34 ^4.35 ^4.36 ^4.37 ^4.38 ^4.39 ^4.40 ^4.41 ^4.42 ^4.43 ^4.44 ^4.45 ^4.46 ^4.47 ^4.48 ^4.49 ^4.50 ^4.51 ^4.52 ^4.53 ^4.54 ^4.55 ^4.56 ^4.57 ^4.58 Tsen, G et al. (1995) Agrin is a heparan sulfate proteoglycan. J. Biol. Chem. 270 3392-9 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Sallum, CO et al. (2007) Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain. Biochemistry 46 9541-50 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Gesemann, M et al. (1996) Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor. Neuron 16 755-67 PubMed GONUTS page
↑ Winzen, U et al. (2003) Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters. J. Biol. Chem. 278 30106-14 PubMed GONUTS page
↑ Scotton, P et al. (2006) Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrin. J. Biol. Chem. 281 36835-45 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Koulen, P et al. (1999) Expression, distribution and ultrastructural localization of the synapse-organizing molecule agrin in the mature avian retina. Eur. J. Neurosci. 11 4188-96 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 Annies, M et al. (2006) Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites. Mol. Cell. Neurosci. 31 515-24 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Ramseger, R et al. (2009) Transmembrane form agrin-induced process formation requires lipid rafts and the activation of Fyn and MAPK. J. Biol. Chem. 284 7697-705 PubMed GONUTS page

[PMID:9184982-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 ^1.15 ^1.16 ^1.17 ^1.18 ^1.19 ^1.20 ^1.21 ^1.22 ^1.23 ^1.24 ^1.25 ^1.26 ^1.27 ^1.28 ^1.29 Halfter, W et al. (1997) Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways. J. Comp. Neurol. 383 1-17 PubMed GONUTS page

[PMID:9151673-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 ^2.19 ^2.20 ^2.21 ^2.22 ^2.23 ^2.24 ^2.25 ^2.26 ^2.27 ^2.28 ^2.29 ^2.30 ^2.31 ^2.32 ^2.33 ^2.34 ^2.35 ^2.36 ^2.37 ^2.38 ^2.39 ^2.40 ^2.41 ^2.42 Denzer, AJ et al. (1997) Agrin binds to the nerve-muscle basal lamina via laminin. J. Cell Biol. 137 671-83 PubMed GONUTS page

[PMID:8522611-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 ^3.21 ^3.22 ^3.23 ^3.24 ^3.25 ^3.26 ^3.27 ^3.28 ^3.29 ^3.30 ^3.31 ^3.32 ^3.33 ^3.34 ^3.35 ^3.36 ^3.37 ^3.38 ^3.39 ^3.40 ^3.41 ^3.42 ^3.43 ^3.44 ^3.45 ^3.46 ^3.47 ^3.48 ^3.49 Denzer, AJ et al. (1995) An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. J. Cell Biol. 131 1547-60 PubMed GONUTS page

[PMID:7852425-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 ^4.15 ^4.16 ^4.17 ^4.18 ^4.19 ^4.20 ^4.21 ^4.22 ^4.23 ^4.24 ^4.25 ^4.26 ^4.27 ^4.28 ^4.29 ^4.30 ^4.31 ^4.32 ^4.33 ^4.34 ^4.35 ^4.36 ^4.37 ^4.38 ^4.39 ^4.40 ^4.41 ^4.42 ^4.43 ^4.44 ^4.45 ^4.46 ^4.47 ^4.48 ^4.49 ^4.50 ^4.51 ^4.52 ^4.53 ^4.54 ^4.55 ^4.56 ^4.57 ^4.58 Tsen, G et al. (1995) Agrin is a heparan sulfate proteoglycan. J. Biol. Chem. 270 3392-9 PubMed GONUTS page

[PMID:17649979-5] 5.0 ^5.1 ^5.2 Sallum, CO et al. (2007) Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain. Biochemistry 46 9541-50 PubMed GONUTS page

[PMID:8607994-6] 6.0 ^6.1 ^6.2 ^6.3 Gesemann, M et al. (1996) Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor. Neuron 16 755-67 PubMed GONUTS page

[PMID:12773545-7] Winzen, U et al. (2003) Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters. J. Biol. Chem. 278 30106-14 PubMed GONUTS page

[PMID:17012237-8] Scotton, P et al. (2006) Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrin. J. Biol. Chem. 281 36835-45 PubMed GONUTS page

[PMID:10594644-9] 9.0 ^9.1 ^9.2 ^9.3 Koulen, P et al. (1999) Expression, distribution and ultrastructural localization of the synapse-organizing molecule agrin in the mature avian retina. Eur. J. Neurosci. 11 4188-96 PubMed GONUTS page

[PMID:16364653-10] 10.0 ^10.1 ^10.2 Annies, M et al. (2006) Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites. Mol. Cell. Neurosci. 31 515-24 PubMed GONUTS page

[PMID:19139104-11] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Ramseger, R et al. (2009) Transmembrane form agrin-induced process formation requires lipid rafts and the activation of Fyn and MAPK. J. Biol. Chem. 284 7697-705 PubMed GONUTS page

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CHICK:AGRIN

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