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CANFA:ANXA2
Contents
| Species (Taxon ID) | Canis familiaris (Dog) (Canis lupus familiaris). (9615) | |
| Gene Name(s) | ANXA2 (synonyms: ANX2) | |
| Protein Name(s) | Annexin A2
Annexin-2 | |
| External Links | ||
| UniProt | Q6TEQ7 | |
| EMBL | AY422991 | |
| RefSeq | NP_001002961.1 | |
| UniGene | Cfa.138 | |
| ProteinModelPortal | Q6TEQ7 | |
| SMR | Q6TEQ7 | |
| DIP | DIP-44616N | |
| IntAct | Q6TEQ7 | |
| MINT | MINT-3375172 | |
| STRING | 9615.ENSCAFP00000024537 | |
| PaxDb | Q6TEQ7 | |
| PRIDE | Q6TEQ7 | |
| Ensembl | ENSCAFT00000026423 | |
| GeneID | 403435 | |
| KEGG | cfa:403435 | |
| CTD | 302 | |
| eggNOG | NOG259189 | |
| GeneTree | ENSGT00760000118972 | |
| HOGENOM | HOG000158803 | |
| HOVERGEN | HBG061815 | |
| InParanoid | Q6TEQ7 | |
| KO | K17092 | |
| OMA | FIQQDTK | |
| OrthoDB | EOG74XS72 | |
| TreeFam | TF105452 | |
| NextBio | 20816953 | |
| Proteomes | UP000002254 | |
| GO | GO:0005604 GO:0005509 GO:0005544 GO:0004859 | |
| Gene3D | 1.10.220.10 | |
| InterPro | IPR001464 IPR018502 IPR018252 IPR002389 | |
| PANTHER | PTHR10502:SF18 | |
| Pfam | PF00191 | |
| PRINTS | PR00196 PR00198 | |
| SMART | SM00335 | |
| PROSITE | PS00223 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005768 |
endosome |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0070382 |
exocytic vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1905602 |
positive regulation of receptor-mediated endocytosis involved in cholesterol transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1905599 |
positive regulation of low-density lipoprotein receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1905597 |
positive regulation of low-density lipoprotein particle receptor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1905581 |
positive regulation of low-density lipoprotein particle clearance |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1903902 |
positive regulation of viral life cycle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0099511 |
voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0072659 |
protein localization to plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060956 |
endocardial cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0052405 |
negative regulation by host of symbiont molecular function |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0052362 |
catabolism by host of symbiont protein |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051928 |
positive regulation of calcium ion transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051290 |
protein heterotetramerization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048146 |
positive regulation of fibroblast proliferation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046790 |
virion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0044794 |
positive regulation by host of viral process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0044730 |
bone sialoprotein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0044548 |
S100 protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0044147 |
negative regulation of development of symbiont involved in interaction with host |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0044090 |
positive regulation of vacuole organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042730 |
fibrinolysis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0036035 |
osteoclast development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032804 |
negative regulation of low-density lipoprotein particle receptor catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032332 |
positive regulation of chondrocyte differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031982 |
vesicle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031340 |
positive regulation of vesicle fusion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031214 |
biomineral tissue development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030199 |
collagen fibril organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019834 |
phospholipase A2 inhibitor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0017137 |
Rab GTPase binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010755 |
regulation of plasminogen activation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006900 |
vesicle budding from membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005546 |
phosphatidylinositol-4,5-bisphosphate binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005544 |
calcium-dependent phospholipid binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005262 |
calcium channel activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0003417 |
growth plate cartilage development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0002020 |
protease binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001934 |
positive regulation of protein phosphorylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001921 |
positive regulation of receptor recycling |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0001786 |
phosphatidylserine binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001765 |
membrane raft assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000052598 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001525 |
angiogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88246 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043086 |
negative regulation of catalytic activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004859 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043086 |
negative regulation of catalytic activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0019834 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051480 |
regulation of cytosolic calcium ion concentration |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0099511 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070588 |
calcium ion transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005262 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004859 |
phospholipase inhibitor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001464 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005544 |
calcium-dependent phospholipid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001464 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008092 |
cytoskeletal protein binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005604 |
basement membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005544 |
calcium-dependent phospholipid binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cao, Z et al. (2008) Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis. Mol. Cell Proteomics 7 1651-67 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 2.21 2.22 2.23 2.24 2.25 2.26 2.27 2.28 2.29 2.30 2.31 2.32 2.33 2.34 2.35 2.36 2.37 2.38 2.39 2.40 2.41 2.42 2.43 2.44 2.45 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
b
c
- GO:0005544 ! calcium-dependent phospholipid binding
- GO:0005262 ! calcium channel activity
- GO:0005509 ! calcium ion binding
- GO:0070588 ! calcium ion transmembrane transport
- Canidae
- Caniformia
- Canis
- Canis familiaris
- Carnivora
- Chordata
- GO:0030199 ! collagen fibril organization
- Craniata
- GO:0005737 ! cytoplasm
- GO:0008092 ! cytoskeletal protein binding
e
n
- GO:0032804 ! negative regulation of low-density lipoprotein particle receptor catabolic process
- GO:0052405 ! negative regulation by host of symbiont molecular function
- GO:0043086 ! negative regulation of catalytic activity
- GO:0044147 ! negative regulation of formation of structure involved in a symbiotic process
- GO:0005634 ! nucleus
p
- GO:0001786 ! phosphatidylserine binding
- GO:0005546 ! phosphatidylinositol-4,5-bisphosphate binding
- GO:0004859 ! phospholipase inhibitor activity
- GO:0019834 ! phospholipase A2 inhibitor activity
- GO:0005886 ! plasma membrane
- GO:1905581 ! positive regulation of low-density lipoprotein particle clearance
- GO:1905597 ! positive regulation of low-density lipoprotein particle receptor binding
- GO:1905599 ! positive regulation of low-density lipoprotein receptor activity
- GO:1905602 ! positive regulation of receptor-mediated endocytosis involved in cholesterol transport
- GO:1903902 ! positive regulation of viral life cycle
- GO:0044794 ! positive regulation by host of viral process
- GO:0001934 ! positive regulation of protein phosphorylation
- GO:0044090 ! positive regulation of vacuole organization
- GO:0051928 ! positive regulation of calcium ion transport
- GO:0032332 ! positive regulation of chondrocyte differentiation
- GO:0031340 ! positive regulation of vesicle fusion
- GO:0001921 ! positive regulation of receptor recycling
- GO:0048146 ! positive regulation of fibroblast proliferation
- GO:0002020 ! protease binding
- GO:0051290 ! protein heterotetramerization
- GO:0072659 ! protein localization to plasma membrane
r
