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CANAL:HIR1
Contents
| Species (Taxon ID) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast). (237561) | |
| Gene Name(s) | HIR1 | |
| Protein Name(s) | Protein HIR1 | |
| External Links | ||
| UniProt | Q5ACW8 | |
| EMBL | AACQ01000031 AACQ01000030 | |
| RefSeq | XP_719545.1 XP_719670.1 | |
| ProteinModelPortal | Q5ACW8 | |
| STRING | 5476.CAL0004571 | |
| GeneID | 3638760 3638796 | |
| KEGG | cal:CaO19.2099 cal:CaO19.9647 | |
| CGD | CAL0004571 | |
| eggNOG | COG2319 | |
| InParanoid | Q5ACW8 | |
| KO | K11293 | |
| OrthoDB | EOG7NCVC9 | |
| Proteomes | UP000000559 | |
| GO | GO:0033186 GO:0000417 GO:0005634 GO:0003682 GO:0016568 GO:0000070 GO:1900239 GO:0006355 GO:0006351 | |
| Gene3D | 2.130.10.10 | |
| InterPro | IPR011494 IPR019015 IPR015943 IPR001680 IPR019775 IPR017986 | |
| Pfam | PF07569 PF09453 PF00400 | |
| SMART | SM00320 | |
| SUPFAM | SSF50978 | |
| PROSITE | PS00678 PS50082 PS50294 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0007059 |
chromosome segregation |
ECO:0000315 |
P |
Figure 2B shows that cells with a mutant HIR1 gene produced more 4N cells than the wild type. Figure 2C shows these 4N cells were due to abnormal nuclear localization, or an abnormality in chromosome segregation. This indicates that HIR1 is needed for proper chromosome segregation. |
complete | |||||
|
involved_in |
GO:0007059 |
chromosome segregation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031935 |
regulation of chromatin silencing |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
P |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0031491 |
nucleosome binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030702 |
chromatin silencing at centromere |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006336 |
DNA replication-independent nucleosome assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0022786 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
F |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0003677 |
DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000790 |
nuclear chromatin |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:99430 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000417 |
HIR complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000070 |
mitotic sister chromatid segregation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000352669 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030448 |
hyphal growth |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000417 |
HIR complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000070 |
mitotic sister chromatid segregation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000775 |
chromosome, centromeric region |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0030702 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006351 |
transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Stevenson, JS & Liu, H (2013) Nucleosome assembly factors CAF-1 and HIR modulate epigenetic switching frequencies in an H3K56 acetylation-associated manner in Candida albicans. Eukaryotic Cell 12 591-603 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Jenull, S et al. (2017) The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals. Sci Rep 7 8308 PubMed GONUTS page
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