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CAEEL:Q94252

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Lipase (ECO:0000256 with PIRNR:PIRNR000862)
External Links
UniProt Q94252
EMBL FO081056
PIR G89074
RefSeq NP_504662.1
UniGene Cel.3151
ProteinModelPortal Q94252
SMR Q94252
STRING 6239.K04A8.5
MEROPS S33.B07
PRIDE Q94252
EnsemblMetazoa K04A8.5
GeneID 179046
KEGG cel:CELE_K04A8.5
UCSC K04A8.5
CTD 179046
WormBase K04A8.5
eggNOG COG0596
GeneTree ENSGT00550000074328
HOGENOM HOG000240694
InParanoid Q94252
OMA KYFALAP
OrthoDB EOG71RXJN
PhylomeDB Q94252
NextBio 903670
Proteomes UP000001940
GO GO:0004806
GO:0008340
GO:0016239
GO:0019433
Gene3D 3.40.50.1820
InterPro IPR029058
IPR000073
IPR006693
IPR025483
Pfam PF04083
PF00561
PIRSF PIRSF000862
SUPFAM SSF53474

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0010508

positive regulation of autophagy

PMID:23392608[1]

IDA: Inferred from Direct Assay

P

Figure 2(A). LIPL-4 activates autophagy.

complete
CACAO 6994

GO:0005737

cytoplasm

PMID:23392608[1]

IDA: Inferred from Direct Assay

C

Supplemental Fig. S4A - The LIPL-4∷TagRFP protein fusion is observed in cytoplasmic bodies resembling autophagic granules.

complete
CACAO 6996

GO:0004806

triglyceride lipase activity

PMID:21906946[2]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:23392608[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006629

lipid metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006693

P

Seeded From UniProt

complete

GO:0008340

determination of adult lifespan

PMID:21906946[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0010508

positive regulation of autophagy

PMID:23392608[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0016042

lipid catabolic process

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0442

P

Seeded From UniProt

complete

GO:0016239

positive regulation of macroautophagy

PMID:21906946[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016787

hydrolase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

GO:0016788

hydrolase activity, acting on ester bonds

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR025483

F

Seeded From UniProt

complete

GO:0019433

triglyceride catabolic process

PMID:21906946[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 O'Rourke, EJ et al. (2013) ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. Genes Dev. 27 429-40 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Lapierre, LR et al. (2011) Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr. Biol. 21 1507-14 PubMed GONUTS page