It is now the 1st OPEN Period for CACAO Fall 2017! It will end on Sunday September 24, 2017 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

CAEEL:Q2L6Y4

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Protein OGT-1, isoform b (ECO:0000313 with EMBL:CCD61615.1)
External Links
UniProt Q2L6Y4
EMBL FO080149
RefSeq NP_001040861.1
UniGene Cel.16882
ProteinModelPortal Q2L6Y4
SMR Q2L6Y4
EnsemblMetazoa K04G7.3b
GeneID 176000
KEGG cel:CELE_K04G7.3
UCSC K04G7.3a
CTD 176000
WormBase K04G7.3b
GeneTree ENSGT00550000074327
HOGENOM HOG000003765
KO K09667
NextBio 890678
Proteomes UP000001940
ExpressionAtlas Q2L6Y4
GO GO:0005634
GO:0048471
GO:0016262
GO:0004722
GO:0040024
GO:0006112
GO:0005977
GO:0019915
GO:0006470
GO:0006493
GO:0000003
GO:0006048
Gene3D 1.25.40.10
InterPro IPR029489
IPR013026
IPR011990
IPR019734
Pfam PF13844
SMART SM00028
PROSITE PS50005
PS50293

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

PMID:21441213[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724
WB:WBVar00092687
WB:WBVar00250065

P

Seeded From UniProt

complete

GO:0004722

protein serine/threonine phosphatase activity

PMID:16882729[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724

F

Seeded From UniProt

complete

GO:0005634

nucleus

PMID:9083068[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005977

glycogen metabolic process

PMID:16882729[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724

P

Seeded From UniProt

complete

GO:0006048

UDP-N-acetylglucosamine biosynthetic process

PMID:9083068[3]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O15294

P

Seeded From UniProt

complete

GO:0006112

energy reserve metabolic process

PMID:16051707[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724

P

Seeded From UniProt

complete

GO:0006470

protein dephosphorylation

PMID:16882729[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724

P

Seeded From UniProt

complete

GO:0006493

protein O-linked glycosylation

PMID:16051707[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724

P

Seeded From UniProt

complete

GO:0006493

protein O-linked glycosylation

PMID:21441213[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724
WB:WBVar00250065

P

Seeded From UniProt

complete

GO:0016262

protein N-acetylglucosaminyltransferase activity

PMID:16051707[4]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

complete

GO:0016262

protein N-acetylglucosaminyltransferase activity

PMID:9083068[3]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O15294

F

Seeded From UniProt

complete

GO:0019915

lipid storage

PMID:16882729[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091724

P

Seeded From UniProt

complete

GO:0040024

dauer larval development

PMID:16051707[4]

IGI: Inferred from Genetic Interaction

WB:WBGene00000898

P

Seeded From UniProt

complete

GO:0048471

perinuclear region of cytoplasm

PMID:9083068[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Mondoux, MA et al. (2011) O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans. Genetics 188 369-82 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Forsythe, ME et al. (2006) Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer. Proc. Natl. Acad. Sci. U.S.A. 103 11952-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Lubas, WA et al. (1997) O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats. J. Biol. Chem. 272 9316-24 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Hanover, JA et al. (2005) A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout. Proc. Natl. Acad. Sci. U.S.A. 102 11266-71 PubMed GONUTS page