CAEEL:O45100

Species (Taxon ID)	Caenorhabditis elegans. (6239)
Gene Name(s)	mec-17 (ECO:0000255 with HAMAP-Rule:MF_03130)
Protein Name(s)	Alpha-tubulin N-acetyltransferase 1 (ECO:0000255 with HAMAP-Rule:MF_03130) Alpha-TAT 1 (ECO:0000255 with HAMAP-Rule:MF_03130) TAT 1 (ECO:0000255 with HAMAP-Rule:MF_03130) Mechanosensory abnormality protein 17 (ECO:0000255 with HAMAP-Rule:MF_03130)
External Links
UniProt	O45100
EMBL	FO081188
PIR	T32979
RefSeq	NP_501337.1
UniGene	Cel.12810
ProteinModelPortal	O45100
SMR	O45100
STRING	6239.F57H12.7
PaxDb	O45100
PRIDE	O45100
EnsemblMetazoa	F57H12.7
GeneID	177596
KEGG	cel:CELE_F57H12.7
UCSC	F57H12.7
CTD	177596
WormBase	F57H12.7
eggNOG	NOG249793
HOGENOM	HOG000021174
InParanoid	O45100
OMA	MQVNADL
OrthoDB	EOG76739W
PhylomeDB	O45100
NextBio	897516
Proteomes	UP000001940
GO	GO:0004468 GO:0019799 GO:0071929 GO:0042490 GO:0048666 GO:0006473 GO:0070507 GO:0001966
Gene3D	3.40.630.30
HAMAP	MF_03130
InterPro	IPR016181 IPR007965
PANTHER	PTHR12327
Pfam	PF05301
PROSITE	PS51730

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0019799	tubulin N-acetyltransferase activity	PMID:20829795	ECO:0000315			F		Figure 2. Along with W06B11.1, MEC-17 acetylates alpha tubulin. This was determined by an antibody-binding assay. Mutant C. elegans without W06B11.1 and MEC-17 did not display alpha-tubulin acetylation.	complete CACAO 3598
involved_in	GO:0001966	thigmotaxis	PMID:24846647	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00021059	P		Seeded From UniProt	complete
involved_in	GO:0001966	thigmotaxis	PMID:24846647	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
colocalizes_with	GO:0005874	microtubule	PMID:20829795	ECO:0000305	curator inference used in manual assertion	GO:0019799	C		Seeded From UniProt	complete
involved_in	GO:0042490	mechanoreceptor differentiation	PMID:8187641	ECO:0000315	mutant phenotype evidence used in manual assertion	WB:WBVar00266627	P		Seeded From UniProt	complete
involved_in	GO:0006473	protein acetylation	PMID:20829795	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00021059	P		Seeded From UniProt	complete
enables	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	PMID:20829795	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q22XZ3	F		Seeded From UniProt	complete
involved_in	GO:0001966	thigmotaxis	PMID:20829795	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00021059	P		Seeded From UniProt	complete
involved_in	GO:0001966	thigmotaxis	PMID:20829795	ECO:0000315	mutant phenotype evidence used in manual assertion	WB:WBVar00093292	P		Seeded From UniProt	complete
enables	GO:0019799	tubulin N-acetyltransferase activity	PMID:20829795	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0071929	alpha-tubulin acetylation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913869 PANTHER:PTN000269078 UniProtKB:Q5SQI0 ZFIN:ZDB-GENE-040426-2120	P		Seeded From UniProt	complete
enables	GO:0019799	tubulin N-acetyltransferase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913869 PANTHER:PTN000269078 UniProtKB:Q5SQI0 WB:WBGene00003178 WB:WBGene00021059	F		Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007965	C		Seeded From UniProt	complete
enables	GO:0019799	tubulin N-acetyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007965 InterPro:IPR038746	F		Seeded From UniProt	complete
involved_in	GO:0071929	alpha-tubulin acetylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007965	P		Seeded From UniProt	complete
enables	GO:0019799	tubulin N-acetyltransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.3.1.108	F		Seeded From UniProt	complete
enables	GO:0019799	tubulin N-acetyltransferase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000106988	F		Seeded From UniProt	complete
involved_in	GO:0071929	alpha-tubulin acetylation	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000106988	P		Seeded From UniProt	complete
involved_in	GO:0070507	regulation of microtubule cytoskeleton organization	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000106988	P		Seeded From UniProt	complete
involved_in	GO:0048666	neuron development	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000106988	P		Seeded From UniProt	complete
enables	GO:0016746	transferase activity, transferring acyl groups	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0012	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
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