CAEEL:G5EBZ8

Species (Taxon ID)	Caenorhabditis elegans. (6239)
Gene Name(s)	No Information Provided.
Protein Name(s)	Ack related non-receptor tyrosine kinase (ECO:0000313 with EMBL:CAB65957.1) Protein ARK-1, isoform a (ECO:0000313 with EMBL:CAB05120.2)
External Links
UniProt	G5EBZ8
EMBL	Z82257 AJ271057
PIR	T18802
RefSeq	NP_001255654.1
UniGene	Cel.19487
EnsemblMetazoa	C01C7.1a
GeneID	178218
KEGG	cel:CELE_C01C7.1
CTD	178218
WormBase	C01C7.1a
GeneTree	ENSGT00760000118799
OMA	HIIETKL
NextBio	900214
PRO	PR:G5EBZ8
Proteomes	UP000001940
ExpressionAtlas	G5EBZ8
GO	GO:0005524 GO:0004713 GO:0009792 GO:0042059 GO:0040027
InterPro	IPR000095 IPR011009 IPR000719 IPR017441 IPR001245 IPR011511 IPR001452 IPR008266 IPR020635
Pfam	PF00786 PF07714 PF07653
PRINTS	PR00109
SMART	SM00285 SM00326 SM00219
SUPFAM	SSF50044 SSF56112
PROSITE	PS50108 PS00107 PS50011 PS00109

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00004774	P	Seeded From UniProt	complete
involved_in	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00002992	P	Seeded From UniProt	complete
involved_in	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00002299	P	Seeded From UniProt	complete
involved_in	GO:0040027	negative regulation of vulval development	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00006829	P	Seeded From UniProt	complete
involved_in	GO:0040027	negative regulation of vulval development	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00004829	P	Seeded From UniProt	complete
involved_in	GO:0040027	negative regulation of vulval development	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00001515	P	Seeded From UniProt	complete
involved_in	GO:0040027	negative regulation of vulval development	PMID:10949028^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	WB:WBVar00248949	P	Seeded From UniProt	complete
involved_in	GO:0009792	embryo development ending in birth or egg hatching	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00002335 WB:WBGene00004829	P	Seeded From UniProt	complete
involved_in	GO:0009792	embryo development ending in birth or egg hatching	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00004829	P	Seeded From UniProt	complete
involved_in	GO:0009792	embryo development ending in birth or egg hatching	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00002335	P	Seeded From UniProt	complete
involved_in	GO:0009792	embryo development ending in birth or egg hatching	PMID:10949028^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	WB:WBGene00001515	P	Seeded From UniProt	complete
involved_in	GO:0042127	regulation of cell population proliferation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:87859 PANTHER:PTN001975310 UniProtKB:Q05397	P	Seeded From UniProt	complete
involved_in	GO:0038083	peptidyl-tyrosine autophosphorylation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95481 PANTHER:PTN001975310 RGD:628758 UniProtKB:P00519 UniProtKB:Q14289	P	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001975310 RGD:628758	P	Seeded From UniProt	complete
enables	GO:0004715	non-membrane spanning protein tyrosine kinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000017 MGI:MGI:104908 MGI:MGI:1930958 MGI:MGI:95481 PANTHER:PTN001975310 UniProtKB:P00519 UniProtKB:Q05397 UniProtKB:Q14289 WB:WBGene00002213	F	Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266	F	Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020635	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F	Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266 InterPro:IPR020635	P	Seeded From UniProt	complete
enables	GO:0004715	non-membrane spanning protein tyrosine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.10.2	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P	Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0723	F	Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0829	F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 Hopper, NA et al. (2000) ARK-1 inhibits EGFR signaling in C. elegans. Mol. Cell 6 65-75 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10949028-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 Hopper, NA et al. (2000) ARK-1 inhibits EGFR signaling in C. elegans. Mol. Cell 6 65-75 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CAEEL:G5EBZ8

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