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CAEEL:ERGO1

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) ergo-1 (ECO:0000312 with WormBase:R09A1.1a)
Protein Name(s) Piwi-like protein ergo-1 (ECO:0000255 with RuleBase:RU361178)

Endogenous RNA interference deficient argonaute protein 1 (ECO:0000312 with WormBase:R09A1.1a)

External Links
UniProt O61931
EMBL BX284605
PIR T33275
RefSeq NP_503362.2
UniGene Cel.17334
ProteinModelPortal O61931
SMR O61931
STRING 6239.R09A1.1
EPD O61931
PaxDb O61931
PRIDE O61931
EnsemblMetazoa [example_ID R09A1.1a]
GeneID 178602
KEGG cel:CELE_R09A1.1
UCSC R09A1.1
CTD 178602
WormBase R09A1.1a
eggNOG KOG1041
ENOG410XP07
HOGENOM HOG000016239
InParanoid O61931
KO K11593
OMA DYRGNDR
PhylomeDB O61931
PRO PR:O61931
Proteomes UP000001940
ExpressionAtlas O61931
GO GO:0005737
GO:0017151
GO:0003676
GO:0030422
GO:0006417
GO:0016246
Gene3D 3.30.420.10
InterPro IPR003100
IPR003165
IPR012337
Pfam PF02170
PF02171
SMART SM00949
SM00950
SUPFAM SSF101690
SSF53098
PROSITE PS50821
PS50822

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0030422

production of siRNA involved in RNA interference

PMID:20116306[1]

ECO:0000315

P

Figure 3B

complete
CACAO 7216

involved_in

GO:0090065

regulation of production of siRNA involved in RNA interference

PMID:22548001[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0035197

siRNA binding

PMID:22548001[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030422

production of siRNA involved in RNA interference

PMID:20116306[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016246

RNA interference

PMID:17110334[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0017151

DEAD/H-box RNA helicase binding

PMID:24684931[4]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P90897

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:22548001[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003165
InterPro:IPR036397

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006417

regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0810

P

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gent, JI et al. (2010) Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma. Mol. Cell 37 679-89 PubMed GONUTS page
  2. 2.0 2.1 2.2 Billi, AC et al. (2012) The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs. PLoS Genet. 8 e1002617 PubMed GONUTS page
  3. Yigit, E et al. (2006) Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell 127 747-57 PubMed GONUTS page
  4. Shirayama, M et al. (2014) The Vasa Homolog RDE-12 engages target mRNA and multiple argonaute proteins to promote RNAi in C. elegans. Curr. Biol. 24 845-51 PubMed GONUTS page