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CAEEL:DYHC
Contents
| Species (Taxon ID) | Caenorhabditis elegans. (6239) | |
| Gene Name(s) | dhc-1 | |
| Protein Name(s) | Dynein heavy chain, cytoplasmic
Dynein heavy chain, cytosolic DYHC | |
| External Links | ||
| UniProt | Q19020 | |
| EMBL | L33260 FO080510 | |
| PIR | D87755 | |
| RefSeq | NP_491363.1 | |
| UniGene | Cel.19011 | |
| ProteinModelPortal | Q19020 | |
| BioGrid | 37511 | |
| STRING | 6239.T21E12.4 | |
| PaxDb | Q19020 | |
| PRIDE | Q19020 | |
| EnsemblMetazoa | T21E12.4 | |
| GeneID | 172041 | |
| KEGG | cel:CELE_T21E12.4 | |
| UCSC | T21E12.4 | |
| CTD | 172041 | |
| WormBase | T21E12.4 | |
| eggNOG | COG5245 | |
| GeneTree | ENSGT00760000118964 | |
| HOGENOM | HOG000176055 | |
| InParanoid | Q19020 | |
| KO | K10413 | |
| OMA | NRWVKEI | |
| OrthoDB | EOG76471R | |
| PhylomeDB | Q19020 | |
| NextBio | 873787 | |
| PRO | PR:Q19020 | |
| Proteomes | UP000001940 | |
| GO | GO:0005938 GO:0005737 GO:0030286 GO:0005874 GO:0005635 GO:0005819 GO:0000922 GO:0005524 GO:0016887 GO:0003777 GO:0051296 GO:0048814 GO:0008090 GO:0051932 GO:0048489 | |
| Gene3D | 3.40.50.300 | |
| InterPro | IPR003593 IPR011704 IPR026983 IPR024743 IPR024317 IPR004273 IPR013594 IPR013602 IPR027417 | |
| PANTHER | PTHR10676 | |
| Pfam | PF07728 PF12780 PF08385 PF08393 PF03028 PF12777 | |
| SMART | SM00382 | |
| SUPFAM | SSF52540 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0051293 |
establishment of spindle localization |
IMP: Inferred from Mutant Phenotype |
P |
Figure 4. |
complete | |||
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
complete | |||
| GO:0000922 |
spindle pole |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0003774 |
motor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
complete | |||
| GO:0003777 |
microtubule motor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
complete | |||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
complete | |||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
complete | |||
| GO:0005635 |
nuclear envelope |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
complete | |||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0005819 |
spindle |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0005819 |
spindle |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0005856 |
cytoskeleton |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
complete | |||
| GO:0005856 |
cytoskeleton |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
complete | |||
| GO:0005874 |
microtubule |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
complete | |||
| GO:0005938 |
cell cortex |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0007018 |
microtubule-based movement |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
complete | |||
| GO:0007399 |
nervous system development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
complete | |||
| GO:0008090 |
retrograde axon cargo transport |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
complete | |||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
complete | |||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
complete | |||
| GO:0016887 |
ATPase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
complete | |||
| GO:0030286 |
dynein complex |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
complete | |||
| GO:0030286 |
dynein complex |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
complete | |||
| GO:0048489 |
synaptic vesicle transport |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0048814 |
regulation of dendrite morphogenesis |
IGI: Inferred from Genetic Interaction |
WB:WBGene00016611 |
P |
Seeded From UniProt |
complete | ||
| GO:0048814 |
regulation of dendrite morphogenesis |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0051293 |
establishment of spindle localization |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0051296 |
establishment of meiotic spindle orientation |
IGI: Inferred from Genetic Interaction |
WB:WBGene00006840 |
P |
Seeded From UniProt |
complete | ||
| GO:0051296 |
establishment of meiotic spindle orientation |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00094697 |
P |
Seeded From UniProt |
complete | ||
| GO:0051932 |
synaptic transmission, GABAergic |
IGI: Inferred from Genetic Interaction |
WB:WBGene00003047 |
P |
Seeded From UniProt |
complete | ||
| GO:0051932 |
synaptic transmission, GABAergic |
IGI: Inferred from Genetic Interaction |
WB:WBGene00006762 |
P |
Seeded From UniProt |
complete | ||
| GO:0051932 |
synaptic transmission, GABAergic |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kotak, S et al. (2012) Cortical dynein is critical for proper spindle positioning in human cells. J. Cell Biol. 199 97-110 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 van der Voet, M et al. (2009) NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha. Nat. Cell Biol. 11 269-77 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Schmidt, DJ et al. (2005) Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations. Mol. Biol. Cell 16 1200-12 PubMed GONUTS page
- ↑ Arimoto, M et al. (2011) The Caenorhabditis elegans JIP3 protein UNC-16 functions as an adaptor to link kinesin-1 with cytoplasmic dynein. J. Neurosci. 31 2216-24 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Locke, CJ et al. (2006) Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. Brain Res. 1120 23-34 PubMed GONUTS page
- ↑ 6.0 6.1 Aguirre-Chen, C et al. (2011) C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites. Development 138 507-18 PubMed GONUTS page
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