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CAEEL:D0VWM8

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Protein TDP-1, isoform c (ECO:0000313 with EMBL:CBH29662.1)
External Links
UniProt D0VWM8
EMBL Z49910
RefSeq NP_001254189.1
UniGene Cel.15106
ProteinModelPortal D0VWM8
SMR D0VWM8
PaxDb D0VWM8
EnsemblMetazoa F44G4.4c
GeneID 174436
KEGG cel:CELE_F44G4.4
CTD 174436
WormBase F44G4.4c
eggNOG NOG145464
GeneTree ENSGT00730000110584
HOGENOM HOG000016692
InParanoid D0VWM8
OMA KHNSSRQ
PRO PR:D0VWM8
Proteomes UP000001940
ExpressionAtlas D0VWM8
GO GO:0005634
GO:0000166
GO:0003727
Gene3D 3.30.70.330
InterPro IPR012677
IPR000504
Pfam PF00076
SMART SM00360
PROSITE PS50102

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006972

hyperosmotic response

PMID:22792076[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22792076[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006979

response to oxidative stress

PMID:22792076[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:22792076[1]

ECO:0000316

genetic interaction evidence used in manual assertion

WB:WBGene00000898

P

has_regulation_target:(WB:WBGene00004932)

Seeded From UniProt

complete

involved_in

GO:0006972

hyperosmotic response

PMID:22792076[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006979

response to oxidative stress

PMID:22792076[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006979

response to oxidative stress

PMID:22792076[1]

ECO:0000316

genetic interaction evidence used in manual assertion

WB:WBGene00000898

P

Seeded From UniProt

complete

involved_in

GO:0008340

determination of adult lifespan

PMID:22792076[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008340

determination of adult lifespan

PMID:22792076[1]

ECO:0000316

genetic interaction evidence used in manual assertion

WB:WBGene00000898

P

Seeded From UniProt

complete

enables

GO:0003727

single-stranded RNA binding

PMID:15826655[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21611156[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(WBbt:0006804)

Seeded From UniProt

complete

part_of

GO:1990904

ribonucleoprotein complex

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001215
FB:FBgn0004237
FB:FBgn0004838
MGI:MGI:1916394
PANTHER:PTN002689974
UniProtKB:P09651
UniProtKB:P19338
UniProtKB:P22626
UniProtKB:Q14103
UniProtKB:Q96EP5
UniProtKB:Q99729

C

Seeded From UniProt

complete

involved_in

GO:0070935

3'-UTR-mediated mRNA stabilization

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002691014
UniProtKB:Q13148

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002691014
RGD:1310906

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002691014
UniProtKB:Q13148

C

Seeded From UniProt

complete

enables

GO:0003730

mRNA 3'-UTR binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002691014
UniProtKB:Q13148

F

Seeded From UniProt

complete

enables

GO:0003727

single-stranded RNA binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002691014
WB:WBGene00006514

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104819
MGI:MGI:1330294
MGI:MGI:893588
MGI:MGI:97286
PANTHER:PTN002689974
RGD:1306751
RGD:1310403
RGD:1310906
RGD:3153
RGD:69234
SGD:S000003391
SGD:S000005483
TAIR:locus:2019622
TAIR:locus:2076096
TAIR:locus:2079874
TAIR:locus:2083810
TAIR:locus:2122009
TAIR:locus:2159401
TAIR:locus:2179939
UniProtKB:P19338
UniProtKB:P22626
UniProtKB:P38159
UniProtKB:P62995
UniProtKB:Q03250
UniProtKB:Q13148
UniProtKB:Q14103
UniProtKB:Q9SVM8

F

Seeded From UniProt

complete

enables

GO:0003690

double-stranded DNA binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002691014
UniProtKB:Q13148

F

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000504
InterPro:IPR035979

F

Seeded From UniProt

complete

involved_in

GO:0008380

RNA splicing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0508

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Vaccaro, A et al. (2012) TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans. PLoS Genet. 8 e1002806 PubMed GONUTS page
  2. Ayala, YM et al. (2005) Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function. J. Mol. Biol. 348 575-88 PubMed GONUTS page
  3. Meissner, B et al. (2011) Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. PLoS ONE 6 e19937 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page