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BRUA2:Q2YRH9

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Species (Taxon ID) Brucella abortus (strain 2308). (359391)
Gene Name(s) No Information Provided.
Protein Name(s) Response regulator receiver (ECO:0000313 with EMBL:CAJ11627.1)
External Links
UniProt Q2YRH9
EMBL AM040264
RefSeq WP_002964749.1
PDB 4G97
PDBsum 4G97
ProteinModelPortal Q2YRH9
EnsemblBacteria CAJ11627
KFJ54017
GeneID 3788198
KEGG bmf:BAB1_1671
PATRIC 17846369
eggNOG COG0784
HOGENOM HOG000144049
OMA NLGHNVI
OrthoDB EOG6P5ZH7
BioCyc BABO359391:GKDV-1714-MONOMER
BMEL359391:GJOQ-1714-MONOMER
Proteomes UP000002719
GO GO:0005622
GO:0000160
InterPro IPR011006
IPR014605
IPR001789
Pfam PF00072
PIRSF PIRSF036400
SMART SM00448
SUPFAM SSF52172
PROSITE PS50110

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044220

host cell perinuclear region of cytoplasm

PMID:23950720[1]

ECO:0000314

C

Figure 3. Confocal micrographs of HeLa cells transfected with Brucella abortus effector protein BspE labeled with HA. BspE was observed forming discrete vesicles in the perinuclear area.

complete
CACAO 10975

GO:0042000

translocation of peptides or proteins into host

PMID:23950720[1]

ECO:0000314

P

Figure 1. TEM1 b-lactamase protein translocation reporter assay. Panel A and B shows percentage of shift in fluorescence emission that correlates with protein Brucella putative effector BAB1_1671 being translocated into 774A.1 host cell (murine cell line). Panel C and D shows representative fluorescence micrographs of protein translocation. Also look Figure S1 and S2.

Figure 2. VirB-dependent translocation of Brucella BsP effectors into J774.A1 cells. Panel A. B. abortus strain 2308 (black bars) or virB9 mutant strain (white bars) expressing the CyaA fusions to the indicated Brucella effector proteins were used to infect J774.A1 cells, and the cAMP level of infected cells was determined.

complete
CACAO 10999

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

bspE

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Myeni, S et al. (2013) Brucella modulates secretory trafficking via multiple type IV secretion effector proteins. PLoS Pathog. 9 e1003556 PubMed GONUTS page