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BRUA2:Q2YLT8

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Species (Taxon ID) Brucella abortus (strain 2308). (359391)
Gene Name(s) No Information Provided.
Protein Name(s) Uncharacterized protein (ECO:0000313 with EMBL:CAJ11904.1)
External Links
UniProt Q2YLT8
EMBL AM040264
RefSeq WP_002967001.1
EnsemblBacteria CAJ11904
KFJ51717
GeneID 3788412
KEGG bmf:BAB1_1948
PATRIC 17846973
eggNOG NOG05040
HOGENOM HOG000289209
OMA YTWKTAY
OrthoDB EOG6KMB6C
BioCyc BABO359391:GKDV-1999-MONOMER
BMEL359391:GJOQ-1999-MONOMER
Proteomes UP000002719
InterPro IPR016181
SUPFAM SSF55729

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044164

host cell cytosol

PMID:23950720[1]

ECO:0000314

C

Figure 3. Confocal micrographs of HeLa cells transfected with Brucella abortus effector protein BspF expressing hemagglutinin displayed a cytosol localization

complete
CACAO 10979

GO:0020002

host cell plasma membrane

PMID:23950720[1]

ECO:0000314

C

Figure 3. Confocal micrographs of HeLa cells transfected with Brucella abortus effector protein BspF expressing hemagglutinin displayed a host plasma membrane localization.

complete
CACAO 10980

GO:0052208

modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction

PMID:23950720[1]

ECO:0000314

P

Figure 1. TEM1 b-lactamase protein translocation reporter assay. Shows translocation of effector protein BspF (BAB1_1948)

Figure 2. VirB-dependent translocation of Brucella BsP effectors into J774.A1 cells. Shows effector protein BspF (BAB1_01948) translocated by T4SS.

Figure 4. A subset of Bsp effectors target the host secretory pathway. Shows that effector protein BspF (BAB1_1948) targets secretory pathway by colocalization with calnexin a marker of ER.

Figure 5. Ectopic expression of BspF (BAB1_1948) in HeLa cells interferes with the host secretory pathway.

Figure 7. Contribution of BspF (BAB1_1948) to inhibition of host cell secretion during infection.

complete
CACAO 11000

Notes

This is bspF

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Myeni, S et al. (2013) Brucella modulates secretory trafficking via multiple type IV secretion effector proteins. PLoS Pathog. 9 e1003556 PubMed GONUTS page