BPT4:RNH

Species (Taxon ID)	Enterobacteria phage T4 (Bacteriophage T4). (10665)
Gene Name(s)	rnh (synonyms: 33.2, das)
Protein Name(s)	Ribonuclease H RNase H
External Links
UniProt	P13319
EMBL	X15818 AF158101
PIR	S05556
RefSeq	NP_049859.1
PDB	1TFR 2IHN 3H7I 3H8J 3H8S 3H8W
PDBsum	1TFR 2IHN 3H7I 3H8J 3H8S 3H8W
ProteinModelPortal	P13319
SMR	P13319
GeneID	1258577
KEGG	vg:1258577
KO	K18950
EvolutionaryTrace	P13319
Proteomes	UP000009087
GO	GO:0003677 GO:0004523 GO:0006260
Gene3D	3.40.50.1010
InterPro	IPR020046 IPR020045 IPR029060
Pfam	PF02739 PF09293
SUPFAM	SSF47807 SSF88723

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004534	5'-3' exoribonuclease activity	PMID:1703156	ECO:0000314			F		FIG. 4. Oligonucleotide products of the 5’ to 3’ DNA exonuclease activity of T4 RNase H	complete CACAO 11942
	GO:0043137	DNA replication, removal of RNA primer	PMID:1703156	ECO:0000314			P		Fig 5 -- Removal of RNA primers radiolabeled with phosphorus was quantified by gel electrophoresis.	complete CACAO 11989
	GO:0004523	RNA-DNA hybrid ribonuclease activity	PMID:11376000	ECO:0000314			F		In figure 3, bands corresponding to radiolabeled RNA oligonucleotides are observed after gel electrophoresis. DNA with replication machinery including a polymerase modified to exclude proofreading activity was incubated with RNAseH and the reaction products were analyzed by gel electrophoresis.	complete CACAO 11990
	GO:0043137	DNA replication, removal of RNA primer	PMID:11376000	ECO:0000314			P		In Figure 4, a reaction mixture including DNA primase was incubated to ensure initiation of DNA replication. After incubation, RNAseH was added and hydrolyzed, radiolabeled primers were observed by gel electrophoresis.	complete CACAO 11991
	GO:0004533	exoribonuclease H activity	PMID:1703156	ECO:0000314			F		FIG. 1	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004519	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004527	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004523	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002421 InterPro:IPR008918 InterPro:IPR020046	F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008918	F		Seeded From UniProt	complete
enables	GO:0017108	5'-flap endonuclease activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038969	F		Seeded From UniProt	complete
involved_in	GO:0033567	DNA replication, Okazaki fragment processing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038969	P		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.26.4	F		Seeded From UniProt	complete
enables	GO:0004527	exonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0269	F		Seeded From UniProt	complete
enables	GO:0004519	endonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P		Seeded From UniProt	complete
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References

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