BPT4:D9IE38

Species (Taxon ID)	Enterobacteria phage T4 (Bacteriophage T4). (10665)
Gene Name(s)	39.2 (ECO:0000313 with EMBL:ADJ39725.1)
Protein Name(s)	Uncharacterized protein 39.2 (ECO:0000313 with EMBL:ADJ39725.1)
External Links
UniProt	D9IE38
EMBL	HM137666
Proteomes	UP000001092
InterPro	IPR013429
Pfam	PF09723
SMART	SM00834
TIGRFAMs	TIGR02605

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:1903332	regulation of protein folding	PMID:22234860	ECO:0001165	colony counting evidence used in manual assertion		P		Gp39.2, which is a bacteriophage T4 protein, is believed to modulate the host's (E. coli) GroEL/GroES chaperone machine, which aids in the correct folding of both host and bacteriophage proteins. Gp39.2 is thought to play a part in correctly folding the E. coli host protein UmuC, which is part of the DNA Polymerase V complex. The authors believe that the GroEL/GroES complex is required for the DNA PolV to work and proofread in the bacteria cell. This relationship between Gp39.2 and DNA PolV is illustrated in Figure 5 where an E. coli mutant (that was only a mutant for isolation purposes for plating) was plated with and without the plasmid containing Gp39.2. The bacterium were then exposed to UV irradiation and were grown with and without arabinose, which showed which mutant bacteria had Gp39.2 in them. The Gp39.2 mutant bacteria were much more frequently seen while plating as opposed to the non-Gp39.2 mutant bacteria.	complete CACAO 13727
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References

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