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BPT4:ALT
Contents
| Species (Taxon ID) | Enterobacteria phage T4 (Bacteriophage T4). (10665) | |
| Gene Name(s) | alt | |
| Protein Name(s) | NAD--protein ADP-ribosyltransferase
Alt protein | |
| External Links | ||
| UniProt | P12726 | |
| EMBL | X15811 AF158101 | |
| PIR | JU0096 | |
| RefSeq | NP_049811.1 | |
| ProteinModelPortal | P12726 | |
| GeneID | 1258760 | |
| Proteomes | UP000009087 | |
| GO | GO:0005576 GO:0019012 GO:0016763 GO:0009405 | |
| InterPro | IPR003540 IPR016225 | |
| Pfam | PF03496 | |
| PIRSF | PIRSF000491 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0019012 |
virion |
ECO:0000314 |
C |
Figure 3. |
complete | |||||
|
Contributes to |
GO:0106274 |
NAD+-protein-arginine ADP-ribosyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Figs 7,8,9. |
complete | |||
| GO:0018120 |
peptidyl-arginine ADP-ribosylation |
ECO:0000315 |
P |
Figure 4. WT MazF is ADP ribosylated after WT T4 phage infection but not after Δalt mutant T4 phage infection, indicating that Alt is an ADP-ribosylase. WT MazF with an arginine at position 4 (R4) is ADP-ribosylated while MazF R4A, where R4 has been replaced by alanine, is not ADP-ribosylated after WT T4 phage infection, indicating that R4 is the amino acid ribosylated by Alt. |
complete | |||||
|
enables |
GO:0003956 |
NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046782 |
regulation of viral transcription |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003956 |
NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003956 |
NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016763 |
transferase activity, transferring pentosyl groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003956 |
NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Clokie, MR et al. (2008) A proteomic approach to the identification of the major virion structural proteins of the marine cyanomyovirus S-PM2. Microbiology (Reading, Engl.) 154 1775-82 PubMed GONUTS page
- ↑ 2.0 2.1 Rohrer, H et al. (1975) ADP-ribosylation of DNA-dependent RNA polymerase of Escherichia coli by an NAD+: protein ADP-ribosyltransferase from bacteriophage T4. Eur. J. Biochem. 60 227-38 PubMed GONUTS page
- ↑ Alawneh, AM et al. (2016) An ADP-ribosyltransferase Alt of bacteriophage T4 negatively regulates the Escherichia coli MazF toxin of a toxin-antitoxin module. Mol. Microbiol. 99 188-98 PubMed GONUTS page
- ↑ Depping, R et al. (2005) The mono-ADP-ribosyltransferases Alt and ModB of bacteriophage T4: target proteins identified. Biochem. Biophys. Res. Commun. 335 1217-23 PubMed GONUTS page
- ↑ 5.0 5.1 Wilkens, K et al. (1997) ADP-ribosylation and early transcription regulation by bacteriophage T4. Adv. Exp. Med. Biol. 419 71-82 PubMed GONUTS page
