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BPP2:HOLIN

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Species (Taxon ID) Enterobacteria phage P2 (Bacteriophage P2). (10679)
Gene Name(s) Y
Protein Name(s) Holin
External Links
UniProt P51773
EMBL AF063097
PIR C55855
RefSeq NP_046764.1
TCDB 1.E.3.1.1
GeneID 1261546
KEGG vg:1261546
Proteomes UP000009092
GO GO:0020002
GO:0016021
GO:0034291
GO:0044660
InterPro IPR007633
Pfam PF04550
ProDom PD064783

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0034291

canonical holin activity

PMID:23335412[1]

ECO:0000314

F

Figure 5

complete
CACAO 10443

GO:0034290

holin activity

PMID:23335412[1]

ECO:0000314

F

Figure 2 displays the results of expressing the holin gene in the lambda phage and testing its lysing abilities on E.coli. The activity assay shows that the holin reduces turbidity in the E.coli and thereby has the lytic properties of a holin.

complete
CACAO 12892

enables

GO:0034291

canonical holin activity

PMID:23335412[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0044660

cytolysis by virus via pore formation in host cell membrane

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0034291

P

Seeded From UniProt

complete

involved_in

GO:0019835

cytolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0204

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1032
UniProtKB-KW:KW-1030
UniProtKB-SubCell:SL-0373

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1043

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 To, KH et al. (2013) Functional analysis of a class I holin, P2 Y. J. Bacteriol. 195 1346-55 PubMed GONUTS page