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BPDP1:ALYS

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Species (Taxon ID) Pneumococcus phage Dp-1 (Bacteriophage Dp-1). (59241)
Gene Name(s) PAL
Protein Name(s) Lysin

Cell wall hydrolase Lytic amidase N-acetylmuramoyl-L-alanine amidase

External Links
UniProt O03979
EMBL Z93946
RefSeq YP_004306947.1
ProteinModelPortal O03979
SMR O03979
GeneID 10358655
GO GO:0044158
GO:0008745
GO:0071555
GO:0019835
GO:0042742
Gene3D 3.90.1720.10
InterPro IPR018337
IPR000064
IPR008044
Pfam PF05382
PF01473
PROSITE PS51170

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044659

cytolysis by virus of host cell

PMID:11739958[1]

ECO:0000314

P

Figure 1 shows Pal induced lysis of a large number of Streptococcus pneumoniae strains. Figure 2 (B-D) also shows lysis compared to the control cells (A).

complete
CACAO 10856

involved_in

GO:0044659

cytolysis by virus of host cell

PMID:11739958[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008745

N-acetylmuramoyl-L-alanine amidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.1.28

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0081

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0081

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0019835

cytolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0081

P

Seeded From UniProt

complete

involved_in

GO:0071555

cell wall organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0961

P

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0081

P

Seeded From UniProt

complete

part_of

GO:0044158

host cell wall

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0424

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Loeffler, JM et al. (2001) Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase. Science 294 2170-2 PubMed GONUTS page