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BOVIN:TPPP

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) TPPP
Protein Name(s) Tubulin polymerization-promoting protein

TPPP 25 kDa brain-specific protein p25-alpha

External Links
UniProt Q27957
EMBL X85738
BC133343
PIR S58769
RefSeq NP_776401.1
UniGene Bt.42
ProteinModelPortal Q27957
SMR Q27957
BioGrid 158347
IntAct Q27957
MINT MINT-3387832
ChEMBL CHEMBL2366491
PRIDE Q27957
Ensembl ENSBTAT00000064550
GeneID 280968
KEGG bta:280968
CTD 11076
eggNOG NOG271804
GeneTree ENSGT00390000014993
HOGENOM HOG000260314
HOVERGEN HBG036683
InParanoid Q27957
OMA IHGDTRA
OrthoDB EOG7NGQDH
TreeFam TF314440
NextBio 20805076
Proteomes UP000009136
GO GO:0005737
GO:0005874
GO:0005634
GO:0048471
GO:0008017
GO:0015631
GO:0001578
GO:0046785
GO:0031334
GO:0032273
InterPro IPR008907
PANTHER PTHR12932
Pfam PF05517

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O94811

C

Seeded From UniProt

complete

involved_in

GO:0046785

microtubule polymerization

PMID:12093283[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032273

positive regulation of protein polymerization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O94811

P

Seeded From UniProt

complete

involved_in

GO:0031334

positive regulation of protein complex assembly

PMID:12093283[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

PMID:12093283[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008017

microtubule binding

PMID:12093283[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

PMID:12093283[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

colocalizes_with

GO:0005874

microtubule

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O94811

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O94811

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O94811

C

Seeded From UniProt

complete

involved_in

GO:0046785

microtubule polymerization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266417
MGI:MGI:1920198
PANTHER:PTN000309419
UniProtKB:O94811
UniProtKB:Q27957

P

Seeded From UniProt

complete

involved_in

GO:0032273

positive regulation of protein polymerization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000309419
UniProtKB:O94811

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000309419
UniProtKB:O94811
UniProtKB:P59282
UniProtKB:Q27957
UniProtKB:Q9BW30

F

Seeded From UniProt

complete

colocalizes_with

GO:0005874

microtubule

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1920198
PANTHER:PTN000309419
UniProtKB:O94811

C

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266417
PANTHER:PTN000309419
UniProtKB:O94811
UniProtKB:P59282
UniProtKB:Q27957
UniProtKB:Q9BW30

P

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030792

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030792

F

Seeded From UniProt

complete

involved_in

GO:0046785

microtubule polymerization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030792

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Hlavanda, E et al. (2002) Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations. Biochemistry 41 8657-64 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page