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BOVIN:PARG

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) PARG
Protein Name(s) Poly(ADP-ribose) glycohydrolase
External Links
UniProt O02776
EMBL U78975
RefSeq NP_776563.1
UniGene Bt.106829
STRING 9913.ENSBTAP00000031225
BindingDB O02776
ChEMBL CHEMBL4279
PRIDE O02776
GeneID 281377
KEGG bta:281377
CTD 8505
eggNOG NOG324088
HOGENOM HOG000168457
HOVERGEN HBG053510
InParanoid O02776
KO K07759
BRENDA 3.2.1.143
NextBio 20805381
Proteomes UP000009136
GO GO:0005634
GO:0004649
GO:0005975
InterPro IPR007724
PANTHER PTHR12837
Pfam PF05028

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004649

poly(ADP-ribose) glycohydrolase activity

PMID:9074616[1]

ECO:0000314

F

Figure 1 shows autoradiographic evaluation of PARG activity. The Poly(ADP-ribose) glycohydrolase (PARG) was purified from calf thymus

complete
CACAO 8908

involved_in

GO:1990966

ATP generation from poly-ADP-D-ribose

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q86W56

P

Seeded From UniProt

complete

enables

GO:0004649

poly(ADP-ribose) glycohydrolase activity

PMID:9074616[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:1990966

ATP generation from poly-ADP-D-ribose

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000303269
UniProtKB:Q86W56

P

Seeded From UniProt

complete

involved_in

GO:0009225

nucleotide-sugar metabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000303269
WB:WBGene00004051
WB:WBGene00004052

P

Seeded From UniProt

complete

involved_in

GO:0006282

regulation of DNA repair

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000303269
UniProtKB:Q9SKB3

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000303269
WB:WBGene00004052

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0023216
MGI:MGI:1347094
PANTHER:PTN000303269
RGD:620387
UniProtKB:Q86W56
WB:WBGene00004051

C

Seeded From UniProt

complete

enables

GO:0004649

poly(ADP-ribose) glycohydrolase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347094
PANTHER:PTN000303269
RGD:620387
UniProtKB:O02776
UniProtKB:Q86W56
UniProtKB:Q9SKB3
WB:WBGene00004051
WB:WBGene00004052

F

Seeded From UniProt

complete

enables

GO:0004649

poly(ADP-ribose) glycohydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007724

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007724

P

Seeded From UniProt

complete

enables

GO:0004649

poly(ADP-ribose) glycohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.143

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bernardi, R et al. (1997) Analysis of poly(ADP-ribose) glycohydrolase activity in nuclear extracts from mammalian cells. Biochim. Biophys. Acta 1338 60-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page