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BORPE:PTLH

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Species (Taxon ID) Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251). (257313)
Gene Name(s) ptlH
Protein Name(s) Type IV secretion system protein PtlH

Pertussis toxin liberation protein H

External Links
UniProt Q7VSX3
EMBL L10720
BX640422
RefSeq NP_882295.1
ProteinModelPortal Q7VSX3
STRING 257313.BP3796
EnsemblBacteria CAE44051
GeneID 2665404
KEGG bpe:BP3796
PATRIC 21161272
eggNOG COG0630
HOGENOM HOG000119934
KO K12083
OMA IRHVENC
OrthoDB EOG6X3W2S
BioCyc BPER257313:BP3796-MONOMER
Proteomes UP000002676
GO GO:0005737
GO:0005524
GO:0009405
GO:0015031
Gene3D 3.40.50.300
InterPro IPR027417
IPR025662
IPR001482
IPR014155
Pfam PF00437
SUPFAM SSF52540
TIGRFAMs TIGR02788

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019534

toxin transporter activity

PMID:9393726[1]

ECO:0000315

F

Figure 5: you can compare the WT to the MT levels of pertussis toxin secretion. The MT cell line have a decreased level of toxin secretion showing that the gene is important for a functional transport system.

complete

part_of

GO:0043684

type IV secretion system complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014155

C

Seeded From UniProt

complete

involved_in

GO:0044097

secretion by the type IV secretion system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014155

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kotob, SI & Burns, DL (1997) Essential role of the consensus nucleotide-binding site of PtlH in secretion of pertussis toxin from Bordetella pertussis. J. Bacteriol. 179 7577-80 PubMed GONUTS page