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BACSU:XHLB
Contents
| Species (Taxon ID) | Bacillus subtilis (strain 168). (224308) | |
| Gene Name(s) | xhlB (synonyms: xpaB) | |
| Protein Name(s) | Holin | |
| External Links | ||
| UniProt | Q99163 | |
| EMBL | Z36941 M63943 L25924 Z70177 AL009126 | |
| PIR | F49754 | |
| RefSeq | NP_389163.1 WP_003232653.1 | |
| STRING | 224308.Bsubs1_010100007096 | |
| TCDB | 1.E.31.1.6 | |
| PaxDb | Q99163 | |
| EnsemblBacteria | CAB13137 | |
| GeneID | 939732 | |
| KEGG | bsu:BSU12800 | |
| PATRIC | 18974311 | |
| HOGENOM | HOG000232121 | |
| OMA | MNTFDKG | |
| PhylomeDB | Q99163 | |
| BioCyc | BSUB:BSU12800-MONOMER | |
| Proteomes | UP000001570 | |
| GO | GO:0016021 | |
| InterPro | IPR006479 | |
| Pfam | PF04688 | |
| ProDom | PD008023 | |
| TIGRFAMs | TIGR01592 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0019835 |
cytolysis |
ECO:0000315 |
P |
Figure 6, contains a graph measuring the OD550 (optical density) over time (hours). The lines on the graph showed various lysis genes. These genes had a combination of mutant strains of xhylA (encodes for putative endolysin), xhlB (encodes for putative holin), or xlyA inject inside of them. According to the graph the lines with with solid triangles (POP1234), solid squares (SK109), and a hallow square (SK110) all decreased in turbidity. Since three of these cultures contained contained strains of either xlyA or xhlB; indicating the bacteria in the culture died due to lysis. This proves holin and endolysin play a major role in lysis. |
complete | |||||
| GO:0016021 |
integral component of membrane |
ECO:0000314 |
C |
PBSX is a late operon that consists of a gene that codes for a putative holin. Figure 2 of the article shows that the turbidity of the bacteria (at 550 nm) in the L8508 and POP1234 cultures decreased after the induction of PBSX, which contributes to the evidence for holin's function as lysis. |
complete | |||||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Krogh, S et al. (1998) Lysis genes of the Bacillus subtilis defective prophage PBSX. J. Bacteriol. 180 2110-7 PubMed GONUTS page
