BACSU:ROCA2

Species (Taxon ID)	Bacillus subtilis (strain 168). (224308)
Gene Name(s)	putC (ECO:0000303 with PMID:22139509) (synonyms: ycgN)
Protein Name(s)	1-pyrroline-5-carboxylate dehydrogenase 2 (ECO:0000305) P5C dehydrogenase 2 (ECO:0000305) L-glutamate gamma-semialdehyde dehydrogenase (ECO:0000255 with HAMAP-Rule:MF_00733)
External Links
UniProt	P94391
EMBL	D50453 AL009126
PIR	A69759
RefSeq	NP_388203.2 WP_003234655.1
ProteinModelPortal	P94391
SMR	P94391
STRING	224308.BSU03210
jPOST	P94391
PaxDb	P94391
PRIDE	P94391
EnsemblBacteria	CAB12115
GeneID	938333
KEGG	bsu:BSU03210
PATRIC	fig|224308.179.peg.335
eggNOG	ENOG4105C26 COG1012
HOGENOM	HOG000271511
InParanoid	P94391
KO	K00294
OMA	ADPHVPF
PhylomeDB	P94391
BioCyc	BSUB:BSU03210-MONOMER
UniPathway	UPA00261
Proteomes	UP000001570
GO	GO:0009898 GO:0003842 GO:0016620 GO:0006537 GO:0010133 GO:0006560
CDD	cd07124
Gene3D	3.40.309.10 3.40.605.10
HAMAP	MF_00733
InterPro	IPR016161 IPR016163 IPR016160 IPR029510 IPR016162 IPR015590 IPR005932
Pfam	PF00171
SUPFAM	SSF53720
TIGRFAMs	TIGR01237
PROSITE	PS00070 PS00687

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0010133	proline catabolic process to glutamate		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 PANTHER:PTN000193023 SGD:S000001079 UniProtKB:Q9I5F6	P		Seeded From UniProt
part_of	GO:0009898	cytoplasmic side of plasma membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 PANTHER:PTN000193023	C		Seeded From UniProt
involved_in	GO:0006560	proline metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 FB:FBgn0037138 PANTHER:PTN000193023 SGD:S000001079 UniProtKB:P10503 UniProtKB:Q9I5F6	P		Seeded From UniProt
enables	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 PANTHER:PTN000193023 SGD:S000001079 UniProtKB:Q9I5F6	F		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015590 InterPro:IPR016160 InterPro:IPR016161 InterPro:IPR016162 InterPro:IPR016163 InterPro:IPR029510	F		Seeded From UniProt
enables	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016163	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015590 InterPro:IPR016160 InterPro:IPR016161 InterPro:IPR016162 InterPro:IPR016163 InterPro:IPR029510	P		Seeded From UniProt
involved_in	GO:0006537	glutamate biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000099061	P		Seeded From UniProt
enables	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000099061	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt
	GO:0004657	proline dehydrogenase activity	PMID:22139509	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Evidence for proline dehydrogenase is in the text, not a figure or table "The addition of L-proline to B. subtilis cultures grown in SMM increased PRODH activity 5-fold from 0.48 ± 0.05 U (mg protein−1) to 2.69 ± 0.21 U (mg protein−1). This increase in PRODH activity was abolished in a putB mutant that possessed an activity of 0.46 ± 0.02 U (mg protein−1) in cells grown in the absence of L-proline and 0.45 ± 0.02 U (mg protein−1) in cells cultivated in the presence of L-proline."	complete CACAO 9945
involved_in	GO:0010133	proline catabolic process to glutamate	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00261	P		Seeded From UniProt
involved_in	GO:0010133	proline catabolic process to glutamate		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 PANTHER:PTN000193023 SGD:S000001079 UniProtKB:Q9I5F6	P		Seeded From UniProt
part_of	GO:0009898	cytoplasmic side of plasma membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 PANTHER:PTN000193023	C		Seeded From UniProt
involved_in	GO:0006560	proline metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 FB:FBgn0037138 PANTHER:PTN000193023 SGD:S000001079 UniProtKB:P10503 UniProtKB:Q9I5F6	P		Seeded From UniProt
enables	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10801 PANTHER:PTN000193023 SGD:S000001079 UniProtKB:Q9I5F6	F		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015590 InterPro:IPR016160 InterPro:IPR016161 InterPro:IPR016162 InterPro:IPR016163 InterPro:IPR029510	F		Seeded From UniProt
enables	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016163	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015590 InterPro:IPR016160 InterPro:IPR016161 InterPro:IPR016162 InterPro:IPR016163 InterPro:IPR029510	P		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt
involved_in	GO:0010133	proline catabolic process to glutamate	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00261	P		Seeded From UniProt
involved_in	GO:0006537	glutamate biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000099061	P		Seeded From UniProt
enables	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000099061	F		Seeded From UniProt
edit table

References

See Help:References for how to manage references in GONUTS.