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BACSU:CHEA

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Species (Taxon ID) Bacillus subtilis (strain 168). (224308)
Gene Name(s) cheA (synonyms: cheN)
Protein Name(s) Chemotaxis protein CheA
External Links
UniProt P29072
EMBL M57894
AL009126
PIR A41653
RefSeq NP_389525.2
ProteinModelPortal P29072
SMR P29072
IntAct P29072
STRING 224308.BSU16430
PaxDb P29072
EnsemblBacteria CAB13516
GeneID 939600
KEGG bsu:BSU16430
PATRIC 18975093
GenoList BSU16430
eggNOG COG0643
HOGENOM HOG000255264
InParanoid P29072
KO K03407
OMA HSGNHVF
OrthoDB EOG62RS8P
PhylomeDB P29072
BioCyc BSUB:BSU16430-MONOMER
BRENDA 2.7.13.3
Proteomes UP000001570
GO GO:0005737
GO:0016020
GO:0005524
GO:0000155
GO:0006928
GO:0006935
Gene3D 1.10.287.560
1.20.120.160
3.30.565.10
3.30.70.1110
InterPro IPR004105
IPR002545
IPR015162
IPR003594
IPR004358
IPR008207
IPR005467
IPR009082
IPR010808
Pfam PF01584
PF02895
PF02518
PF01627
PF07194
PRINTS PR00344
SMART SM00260
SM00387
SM00073
SUPFAM SSF47226
SSF47384
SSF50341
SSF55052
SSF55874
PROSITE PS50851
PS50109
PS50894

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000160

phosphorelay signal transduction system

PMID:1938941[1]

ECO:0000315

P

See Results: Characterization.

complete
CACAO 10376

involved_in

GO:0018106

peptidyl-histidine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004673

P

Seeded From UniProt

complete

GO:0000155

phosphorelay sensor kinase activity

PMID:11553614[2]

ECO:0000315

F

See Figure 1: Phospho-transfer from CheA to wild-type and mutant CheV proteins, and Figure 3: Phospho-transfer between CheA-P and CheB.

complete
CACAO 10497

GO:0071978

bacterial-type flagellum-dependent swarming motility

PMID:25313396[3]

ECO:0000315

P

Figure 4 shows that cheA mutant of B.subtilis shows a significant decrease in swarm radius in comparison to the wild type.

complete
CACAO 13202

involved_in

GO:0018106

peptidyl-histidine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004673

P

Seeded From UniProt

complete

involved_in

GO:0023014

signal transduction by protein phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0000155

P

Seeded From UniProt

complete

enables

GO:0000155

phosphorelay sensor kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004105
InterPro:IPR010808
InterPro:IPR036097
InterPro:IPR037006

F

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004105
InterPro:IPR008207
InterPro:IPR010808
InterPro:IPR036641

P

Seeded From UniProt

complete

enables

GO:0004673

protein histidine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004105
InterPro:IPR010808

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004105

C

Seeded From UniProt

complete

involved_in

GO:0006935

chemotaxis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002545
InterPro:IPR004105
InterPro:IPR036061
InterPro:IPR037006

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002545
InterPro:IPR036061
InterPro:IPR036097

P

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004358

P

Seeded From UniProt

complete

enables

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004358

F

Seeded From UniProt

complete

enables

GO:0004673

protein histidine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.13.3

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0006935

chemotaxis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0145

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Fuhrer, DK & Ordal, GW (1991) Bacillus subtilis CheN, a homolog of CheA, the central regulator of chemotaxis in Escherichia coli. J. Bacteriol. 173 7443-8 PubMed GONUTS page
  2. Karatan, E et al. (2001) Phosphorylation of the response regulator CheV is required for adaptation to attractants during Bacillus subtilis chemotaxis. J. Biol. Chem. 276 43618-26 PubMed GONUTS page
  3. Calvo, RA & Kearns, DB (2015) FlgM is secreted by the flagellar export apparatus in Bacillus subtilis. J. Bacteriol. 197 81-91 PubMed GONUTS page