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ARATH:RIN4

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) RIN4
Protein Name(s) RPM1-interacting protein 4
External Links
UniProt Q8GYN5
EMBL AB026647
CP002686
AK117488
RefSeq NP_189143.2
UniGene At.43082
PDB 2NUD
PDBsum 2NUD
ProteinModelPortal Q8GYN5
BioGrid 7429
DIP DIP-53466N
IntAct Q8GYN5
PaxDb Q8GYN5
PRIDE Q8GYN5
EnsemblPlants AT3G25070.1
GeneID 822098
KEGG ath:AT3G25070
TAIR AT3G25070
eggNOG NOG330720
HOGENOM HOG000030266
InParanoid Q8GYN5
KO K13456
OMA DWDENNP
PhylomeDB Q8GYN5
EvolutionaryTrace Q8GYN5
PMAP-CutDB Q8GYN5
Proteomes UP000006548
ExpressionAtlas Q8GYN5
Genevestigator Q8GYN5
GO GO:0012505
GO:0019897
GO:0016020
GO:0005886
GO:0010204
GO:0009816
GO:0034051
GO:0009626
GO:0006468
GO:0002237
InterPro IPR008700
Pfam PF05627

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0034051

negative regulation of plant-type hypersensitive response

PMID:11955429[1]

ECO:0000315

P

Fig. 5a. shows the rin4 mutant to have less disease progression than the complement and the wild type. 5B. shows the number of spores from the pathogen to be much higher in the rin4 mutants. 5c. shows the expression of PR-1 a protein directly involved in the plant hypersensitive response is higher in rin4 mutants than it is in wild type (Ws-O) and rin4 complements.

complete
CACAO 4242

involved_in

GO:0034051

negative regulation of plant-type hypersensitive response

PMID:11955429[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034051

negative regulation of plant-type hypersensitive response

PMID:20159621[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0019897

extrinsic component of plasma membrane

PMID:22215637[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:15845764[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:11955429[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0010204

defense response signaling pathway, resistance gene-independent

PMID:15935761[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009816

defense response to bacterium, incompatible interaction

PMID:11607554[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009626

plant-type hypersensitive response

PMID:12581527[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

PMID:11955429[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:17317660[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:14506206[9]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0002237

response to molecule of bacterial origin

PMID:15935761[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010204

defense response signaling pathway, resistance gene-independent

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002108974
TAIR:locus:2090250

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002108974
TAIR:locus:2058284
TAIR:locus:2090250
UniProtKB:F4K692

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15845764[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0611

P

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

involved_in

GO:0009626

plant-type hypersensitive response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0381

P

Seeded From UniProt

complete

part_of

GO:0012505

endomembrane system

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0147

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Mackey, D et al. (2002) RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis. Cell 108 743-54 PubMed GONUTS page
  2. Cui, H et al. (2010) Pseudomonas syringae effector protein AvrB perturbs Arabidopsis hormone signaling by activating MAP kinase 4. Cell Host Microbe 7 164-75 PubMed GONUTS page
  3. Elmore, JM et al. (2012) Quantitative proteomics reveals dynamic changes in the plasma membrane during Arabidopsis immune signaling. Mol. Cell Proteomics 11 M111.014555 PubMed GONUTS page
  4. 4.0 4.1 Kim, HS et al. (2005) The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation. Proc. Natl. Acad. Sci. U.S.A. 102 6496-501 PubMed GONUTS page
  5. 5.0 5.1 Kim, MG et al. (2005) Two Pseudomonas syringae type III effectors inhibit RIN4-regulated basal defense in Arabidopsis. Cell 121 749-59 PubMed GONUTS page
  6. Century, KS et al. (1995) NDR1, a locus of Arabidopsis thaliana that is required for disease resistance to both a bacterial and a fungal pathogen. Proc. Natl. Acad. Sci. U.S.A. 92 6597-601 PubMed GONUTS page
  7. Mackey, D et al. (2003) Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance. Cell 112 379-89 PubMed GONUTS page
  8. Benschop, JJ et al. (2007) Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. Mol. Cell Proteomics 6 1198-214 PubMed GONUTS page
  9. Nühse, TS et al. (2003) Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Mol. Cell Proteomics 2 1234-43 PubMed GONUTS page
  10. 10.0 10.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page