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ARATH:PPA26

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) PAP26
Protein Name(s) Bifunctional purple acid phosphatase 26

Acid phosphatase Peroxidase

External Links
UniProt Q949Y3
EMBL AY842026
AC019013
CP002688
AY050812
AY091415
RefSeq NP_198334.1
UniGene At.20088
ProteinModelPortal Q949Y3
SMR Q949Y3
STRING 3702.AT5G34850.1
PaxDb Q949Y3
PRIDE Q949Y3
EnsemblPlants [example_ID AT5G34850.1]
GeneID 833406
Gramene AT5G34850.1
KEGG ath:AT5G34850
TAIR AT5G34850
eggNOG KOG1378
COG1409
HOGENOM HOG000238330
InParanoid Q949Y3
OMA NVNYNIT
PhylomeDB Q949Y3
BRENDA 3.1.3.2
PRO PR:Q949Y3
Proteomes UP000006548
Genevisible Q949Y3
GO GO:0005829
GO:0009505
GO:0005773
GO:0003993
GO:0046872
GO:0004601
GO:0016311
GO:0042744
GO:0055062
Gene3D 2.60.40.380
3.60.21.10
InterPro IPR004843
IPR029052
IPR008963
IPR015914
IPR025733
Pfam PF00149
PF14008
PF16656
SUPFAM SSF49363
SSF56300

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1904097

acid phosphatase complex

PMID:25075326[1]

ECO:0000314

C

The homohexameric organization of PPD1, as revealed by a 1.65 Å resolution crystal structure and confirmed by solution X-ray scattering, is unique among plant PAPs, for which only homodimers have previously been reported. A phosphate anion is bound in a bidentate fashion at the active site, bridging the Fe and Mn atoms in a binding mode similar to that previously reported for sweet potato PAP, which suggests that common features occur in their catalytic mechanisms.

complete
CACAO 11894

involved_in

GO:0055062

phosphate ion homeostasis

PMID:20348213[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009505

plant-type cell wall

PMID:17526915[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21166475[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005773

vacuole

PMID:20348213[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005773

vacuole

PMID:15539469[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005773

vacuole

PMID:15215502[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003993

acid phosphatase activity

PMID:23125358[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003993

acid phosphatase activity

PMID:16244908[8]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003993

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003993

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003993

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003993

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

enables

GO:0003993

acid phosphatase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008963
InterPro:IPR015914
InterPro:IPR039331

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004843

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008963
InterPro:IPR015914

F

Seeded From UniProt

complete

enables

GO:0004601

peroxidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.11.1.7

F

Seeded From UniProt

complete

enables

GO:0003993

acid phosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.2

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0042744

hydrogen peroxide catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0376

P

Seeded From UniProt

complete

part_of

GO:0005773

vacuole

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0926
UniProtKB-SubCell:SL-0272

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0004601

peroxidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0575

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Antonyuk, SV et al. (2014) The structure of a purple acid phosphatase involved in plant growth and pathogen defence exhibits a novel immunoglobulin-like fold. IUCrJ 1 101-9 PubMed GONUTS page
  2. 2.0 2.1 Hurley, BA et al. (2010) The dual-targeted purple acid phosphatase isozyme AtPAP26 is essential for efficient acclimation of Arabidopsis to nutritional phosphate deprivation. Plant Physiol. 153 1112-22 PubMed GONUTS page
  3. Minic, Z et al. (2007) A sub-proteome of Arabidopsis thaliana mature stems trapped on Concanavalin A is enriched in cell wall glycoside hydrolases. J. Exp. Bot. 58 2503-12 PubMed GONUTS page
  4. Ito, J et al. (2011) Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. J. Proteome Res. 10 1571-82 PubMed GONUTS page
  5. Carter, C et al. (2004) The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Plant Cell 16 3285-303 PubMed GONUTS page
  6. Shimaoka, T et al. (2004) Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana. Plant Cell Physiol. 45 672-83 PubMed GONUTS page
  7. Robinson, WD et al. (2012) The secreted purple acid phosphatase isozymes AtPAP12 and AtPAP26 play a pivotal role in extracellular phosphate-scavenging by Arabidopsis thaliana. J. Exp. Bot. 63 6531-42 PubMed GONUTS page
  8. Zhu, H et al. (2005) Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower. Plant Mol. Biol. 59 581-94 PubMed GONUTS page