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ARATH:METK1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) SAM1
Protein Name(s) S-adenosylmethionine synthase 1

AdoMet synthase 1 Methionine adenosyltransferase 1 MAT 1

External Links
UniProt P23686
EMBL M55077
AC022521
CP002684
CP002684
AF325061
AY092955
AF428440
AY052311
AY061895
AY087703
Z17672
Z17762
PIR C86155
JN0131
RefSeq NP_171751.1
NP_849577.1
UniGene At.24731
ProteinModelPortal P23686
SMR P23686
BioGrid 24736
MINT MINT-8064442
SWISS-2DPAGE P99056
PaxDb P23686
PRIDE P23686
EnsemblPlants AT1G02500.1
AT1G02500.2
GeneID 839501
KEGG ath:AT1G02500
TAIR AT1G02500
eggNOG COG0192
HOGENOM HOG000245710
InParanoid P23686
KO K00789
OMA CETQIAY
PhylomeDB P23686
BioCyc ARA:AT1G02500-MONOMER
ARA:GQT-680-MONOMER
MetaCyc:AT1G02500-MONOMER
Reactome REACT_185282
REACT_256117
UniPathway UPA00315
Proteomes UP000006548
Genevestigator P23686
GO GO:0005618
GO:0005829
GO:0016020
GO:0005886
GO:0005524
GO:0046872
GO:0004478
GO:0071281
GO:0009693
GO:0006730
GO:0046686
GO:0009651
GO:0006556
HAMAP MF_00086
InterPro IPR022631
IPR022630
IPR022629
IPR022628
IPR002133
IPR022636
PANTHER PTHR11964
Pfam PF02773
PF02772
PF00438
PIRSF PIRSF000497
SUPFAM SSF55973
TIGRFAMs TIGR01034
PROSITE PS00376
PS00377

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004478

methionine adenosyltransferase activity

PMID:2535470[1]

ECO:0000314

F

Table 1 shows the results of AdoMet Sythetase Assays where the stem extract contained 10 times more AdoMet Sythetase activity than in leaf extract. Along with figure 2(a) which showed increased expression of sam-1 gene in stem extracts compared to leaf extracts.

complete
CACAO 4320

enables

GO:0004478

methionine adenosyltransferase activity

PMID:2535470[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0071281

cellular response to iron ion

PMID:20627899[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046686

response to cadmium ion

PMID:16502469[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:17432890[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009651

response to salt stress

PMID:17916636[5]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:17317660[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21166475[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

PMID:16287169[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004478

methionine adenosyltransferase activity

PMID:16365035[9]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10589
PANTHER:PTN000239344
RGD:3050
RGD:619985
TAIR:locus:2058011
TAIR:locus:2141385
TAIR:locus:2196160
UniProtKB:P9WGV1

C

Seeded From UniProt

complete

enables

GO:0004478

methionine adenosyltransferase activity

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10589
MGI:MGI:2443731
PANTHER:PTN000239344
PomBase:SPBC14F5.05c
RGD:3050
RGD:619985
SGD:S000002910
SGD:S000004170
TAIR:locus:2058011
TAIR:locus:2196160
UniProtKB:P31153
UniProtKB:Q00266

F

Seeded From UniProt

complete

enables

GO:0004478

methionine adenosyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002133
InterPro:IPR022628
InterPro:IPR022629
InterPro:IPR022630
InterPro:IPR022631
InterPro:IPR022636

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002133

F

Seeded From UniProt

complete

involved_in

GO:0006556

S-adenosylmethionine biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002133
InterPro:IPR022628
InterPro:IPR022629
InterPro:IPR022630
InterPro:IPR022631
InterPro:IPR022636

P

Seeded From UniProt

complete

enables

GO:0004478

methionine adenosyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.6

F

Seeded From UniProt

complete

involved_in

GO:0009693

ethylene biosynthetic process

PMID:2535470[1]
PMID:16311726[11]

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006730

one-carbon metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0554

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0006556

S-adenosylmethionine biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00315

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Peleman, J et al. (1989) Strong cellular preference in the expression of a housekeeping gene of Arabidopsis thaliana encoding S-adenosylmethionine synthetase. Plant Cell 1 81-93 PubMed GONUTS page
  2. García, MJ et al. (2010) Ethylene and nitric oxide involvement in the up-regulation of key genes related to iron acquisition and homeostasis in Arabidopsis. J. Exp. Bot. 61 3885-99 PubMed GONUTS page
  3. Sarry, JE et al. (2006) The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses. Proteomics 6 2180-98 PubMed GONUTS page
  4. Mitra, SK et al. (2007) Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques. J. Proteome Res. 6 1933-50 PubMed GONUTS page
  5. Jiang, Y et al. (2007) Comparative proteomic analysis of NaCl stress-responsive proteins in Arabidopsis roots. J. Exp. Bot. 58 3591-607 PubMed GONUTS page
  6. Benschop, JJ et al. (2007) Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. Mol. Cell Proteomics 6 1198-214 PubMed GONUTS page
  7. Ito, J et al. (2011) Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. J. Proteome Res. 10 1571-82 PubMed GONUTS page
  8. Bayer, EM et al. (2006) Arabidopsis cell wall proteome defined using multidimensional protein identification technology. Proteomics 6 301-11 PubMed GONUTS page
  9. Lindermayr, C et al. (2006) Differential inhibition of Arabidopsis methionine adenosyltransferases by protein S-nitrosylation. J. Biol. Chem. 281 4285-91 PubMed GONUTS page
  10. 10.0 10.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  11. Babula, D et al. (2006) Genes involved in biosynthesis and signalisation of ethylene in Brassica oleracea and Arabidopsis thaliana: identification and genome comparative mapping of specific gene homologues. Theor. Appl. Genet. 112 410-20 PubMed GONUTS page