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ARATH:HFA4A
Contents
| Species (Taxon ID) | Arabidopsis thaliana (Mouse-ear cress). (3702) | |
| Gene Name(s) | HSFA4A (synonyms: HSF15, HSF21) | |
| Protein Name(s) | Heat stress transcription factor A-4a
AtHsfA4a AtHsf-15 Heat shock factor protein 21 HSF 21 Heat shock transcription factor 21 HSTF 21 | |
| External Links | ||
| UniProt | O49403 | |
| EMBL | AL021711 AL161549 CP002687 AY125512 BT001049 U68561 | |
| PIR | T05025 | |
| RefSeq | NP_193623.1 | |
| UniGene | At.1951 | |
| ProteinModelPortal | O49403 | |
| SMR | O49403 | |
| STRING | 3702.AT4G18880.1-P | |
| PaxDb | O49403 | |
| PRIDE | O49403 | |
| EnsemblPlants | AT4G18880.1 | |
| GeneID | 827622 | |
| KEGG | ath:AT4G18880 | |
| GeneFarm | 4104 | |
| TAIR | AT4G18880 | |
| eggNOG | COG5169 | |
| HOGENOM | HOG000237979 | |
| InParanoid | O49403 | |
| KO | K09419 | |
| OMA | GTATHEA | |
| PhylomeDB | O49403 | |
| Reactome | REACT_220111 REACT_240287 REACT_249954 REACT_257743 | |
| Proteomes | UP000006548 | |
| Genevestigator | O49403 | |
| GO | GO:0005737 GO:0005634 GO:0043565 GO:0003700 GO:0010200 GO:0009408 GO:0006351 | |
| Gene3D | 1.10.10.10 | |
| InterPro | IPR000232 IPR027725 IPR027709 IPR011991 | |
| PANTHER | PTHR10015 PTHR10015:SF146 | |
| Pfam | PF00447 | |
| PRINTS | PR00056 | |
| SMART | SM00415 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0042538 |
hyperosmotic salinity response |
ECO:0000315 |
P |
Figure 2 has an overexpressor mutant of HSFA4A compared to wild type Arabidopsis thaliana grown in high NaCl media conditions. Overexpressng plants had higher rates of survival, root, and rosette growth in comparison to wild type. Figure 4 shows the growth of a HSFA4A t-DNA knockout mutant grown on high salinity media compared to wild type. The HSFA4A knockout had lower rates of survival and smaller rosette size when compared to wild type. Complementation of the HSFA4A gene had a partial restoration of function seen in larger rosettes and higher survival rates with high concentrations of NaCl. |
complete | |||||
|
involved_in |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
AGI_LocusCode:AT4G18880 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010200 |
response to chitin |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
Missing: with/from | |||
|
involved_in |
GO:0000302 |
response to reactive oxygen species |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061408 |
positive regulation of transcription from RNA polymerase II promoter in response to heat stress |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000001154 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001222 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034605 |
cellular response to heat |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:3045337 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000195882 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000195882 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96238 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Pérez-Salamó, I et al. (2014) The heat shock factor A4A confers salt tolerance and is regulated by oxidative stress and the mitogen-activated protein kinases MPK3 and MPK6. Plant Physiol. 165 319-34 PubMed GONUTS page
- ↑ Libault, M et al. (2007) Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor. Mol. Plant Microbe Interact. 20 900-11 PubMed GONUTS page
- ↑ Riechmann, JL et al. (2000) Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290 2105-10 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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