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ARATH:HEC1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) HEC1 (synonyms: BHLH88, EN118)
Protein Name(s) Transcription factor HEC1

Basic helix-loop-helix protein 88 AtbHLH88 bHLH 88 Protein HECATE 1 Transcription factor EN 118 bHLH transcription factor bHLH088

External Links
UniProt Q9FHA7
EMBL AF488618
AB020742
CP002688
AK228927
RefSeq NP_201507.1
UniGene At.28829
ProteinModelPortal Q9FHA7
SMR Q9FHA7
BioGrid 22083
IntAct Q9FHA7
STRING 3702.AT5G67060.1
PaxDb Q9FHA7
PRIDE Q9FHA7
EnsemblPlants [example_ID AT5G67060.1]
GeneID 836841
Gramene AT5G67060.1
KEGG ath:AT5G67060
TAIR AT5G67060
eggNOG ENOG410IYF0
ENOG410YJCH
HOGENOM HOG000242863
InParanoid Q9FHA7
OMA GVVMKGC
PhylomeDB Q9FHA7
PRO PR:Q9FHA7
Proteomes UP000006548
Genevisible Q9FHA7
GO GO:0005634
GO:0043565
GO:0003700
GO:0048462
GO:0045893
GO:0006355
GO:0006351
GO:0010500
Gene3D 4.10.280.10
InterPro IPR011598
Pfam PF00010
SMART SM00353
SUPFAM SSF47459
PROSITE PS50888

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006351

transcription, DNA-templated

PMID:24187132[1]

ECO:0000314

P

Figure 2 shows that Aurora B phosphorylates the Hec1-N-terminal tail. This phosphorylation causes the regulation of the kinetochore localization of Mps1.

complete
CACAO 11823

involved_in

GO:2000012

regulation of auxin polar transport

PMID:26293302[2]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT1G70940
AGI_LocusCode:AT1G73590

P

Seeded From UniProt

complete

involved_in

GO:0048467

gynoecium development

PMID:26293302[2]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT3G50330
AGI_LocusCode:AT5G09750

P

Seeded From UniProt

complete

involved_in

GO:0048462

carpel formation

PMID:17855426[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:26293302[2]

ECO:0000353

physical interaction evidence used in manual assertion

AGI_LocusCode:AT1G73590

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:26293302[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0010500

transmitting tissue development

PMID:17855426[3]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT3G50330

P

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

PMID:27625656[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:12679534[5]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

enables

GO:0003700

DNA-binding transcription factor activity

PMID:11118137[6]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024097

P

Seeded From UniProt

complete

enables

GO:0046983

protein dimerization activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011598
InterPro:IPR036638

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:11118137[6]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Zhu, T et al. (2013) Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. J. Biol. Chem. 288 36149-59 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Schuster, C et al. (2015) Arabidopsis HECATE genes function in phytohormone control during gynoecium development. Development 142 3343-50 PubMed GONUTS page
  3. 3.0 3.1 Gremski, K et al. (2007) The HECATE genes regulate female reproductive tract development in Arabidopsis thaliana. Development 134 3593-601 PubMed GONUTS page
  4. Boex-Fontvieille, E et al. (2016) An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci 7 1246 PubMed GONUTS page
  5. Heim, MA et al. (2003) The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol. 20 735-47 PubMed GONUTS page
  6. 6.0 6.1 Riechmann, JL et al. (2000) Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290 2105-10 PubMed GONUTS page