ARATH:ARR12

Species (Taxon ID)	Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s)	ARR12
Protein Name(s)	Two-component response regulator ARR12
External Links
UniProt	P62598
EMBL	CP002685 BE522295
RefSeq	NP_180090.6
UniGene	At.19775
ProteinModelPortal	P62598
SMR	P62598
IntAct	P62598
MINT	MINT-8068784
STRING	3702.AT2G25180.1-P
EnsemblPlants	AT2G25180.1
GeneID	817056
KEGG	ath:AT2G25180
GeneFarm	3926
TAIR	AT2G25180
eggNOG	COG2204
HOGENOM	HOG000238840
InParanoid	P62598
KO	K14491
OMA	DIVNSTM
Proteomes	UP000006548
Genevestigator	P62598
GO	GO:0005634 GO:0003682 GO:0003677 GO:0000156 GO:0003700 GO:0071368 GO:0009736 GO:0080022 GO:0031537 GO:0010380 GO:0010082 GO:0080113 GO:0009735 GO:0048364 GO:0048367 GO:0006351
Gene3D	1.10.10.60
InterPro	IPR011006 IPR009057 IPR017930 IPR006447 IPR017053 IPR001005 IPR001789
Pfam	PF00249 PF00072
PIRSF	PIRSF036392
SMART	SM00448
SUPFAM	SSF46689 SSF52172
TIGRFAMs	TIGR01557
PROSITE	PS51294 PS50110

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0010082	regulation of root meristem growth	PMID:23482873^[1]	ECO:0000315			P	Fig 1C "arr12 mutant exhibited enlarged meristem throughout this time period"	complete CACAO 8350
	GO:0080036	regulation of cytokinin mediated signaling pathway	PMID:23482873^[1]	ECO:0000315			P	Figure 2b	complete CACAO 8355
involved_in	GO:0080036	regulation of cytokinin-activated signaling pathway	PMID:23482873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010082	regulation of root meristem growth	PMID:23482873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0080113	regulation of seed growth	PMID:23482873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0080022	primary root development	PMID:18723577^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:At3g16857 AGI_LocusCode:At4g31920	P	Seeded From UniProt	complete
involved_in	GO:0071368	cellular response to cytokinin stimulus	PMID:23482873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048367	shoot system development	PMID:18723577^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:At3g16857 AGI_LocusCode:At4g31920	P	Seeded From UniProt	complete
involved_in	GO:0048364	root development	PMID:23482873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0031537	regulation of anthocyanin metabolic process	PMID:18723577^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:At3g16857 AGI_LocusCode:At4g31920	P	Seeded From UniProt	complete
involved_in	GO:0010492	maintenance of shoot apical meristem identity	PMID:28576846^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:AT3G16857 AGI_LocusCode:AT4G31920	P	Seeded From UniProt	complete
involved_in	GO:0010380	regulation of chlorophyll biosynthetic process	PMID:18723577^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:At3g16857 AGI_LocusCode:At4g31920	P	Seeded From UniProt	complete
involved_in	GO:0010082	regulation of root meristem growth	PMID:23482873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0009736	cytokinin-activated signaling pathway	PMID:18723577^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:At3g16857 AGI_LocusCode:At4g31920	P	Seeded From UniProt	complete
involved_in	GO:0009735	response to cytokinin	PMID:18723577^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:At3g16857 AGI_LocusCode:At4g31920	P	Seeded From UniProt	complete
involved_in	GO:0009735	response to cytokinin	PMID:16227453^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:AT2G25180 AGI_LocusCode:AT3G16857 AGI_LocusCode:AT4G31920	P	Seeded From UniProt	complete
involved_in	GO:0009414	response to water deprivation	PMID:26884175^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	AGI_LocusCode:AT3G16857 AGI_LocusCode:AT4G31920	P	Seeded From UniProt	complete
involved_in	GO:0009414	response to water deprivation	PMID:26884175^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:15173562^[6]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:11118137^[7]	ECO:0000250	sequence similarity evidence used in manual assertion		F	Seeded From UniProt	Missing: with/from
enables	GO:0000156	phosphorelay response regulator activity	PMID:12068096^[8]	ECO:0000250	sequence similarity evidence used in manual assertion		F	Seeded From UniProt	Missing: with/from
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0003700	P	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003700	P	Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001789	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009057 InterPro:IPR017053	F	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017053	F	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017053	P	Seeded From UniProt	complete
involved_in	GO:0009736	cytokinin-activated signaling pathway	PMID:12068096^[8]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0902	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
involved_in	GO:0009736	cytokinin-activated signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0932	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Hill, K et al. (2013) Functional characterization of type-B response regulators in the Arabidopsis cytokinin response. Plant Physiol. 162 212-24 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Argyros, RD et al. (2008) Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development. Plant Cell 20 2102-16 PubMed GONUTS page
↑ Meng, WJ et al. (2017) Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of . Plant Cell 29 1357-1372 PubMed GONUTS page
↑ Mason, MG et al. (2005) Multiple type-B response regulators mediate cytokinin signal transduction in Arabidopsis. Plant Cell 17 3007-18 PubMed GONUTS page
↑ ^5.0 ^5.1 Nguyen, KH et al. (2016) Arabidopsis type B cytokinin response regulators ARR1, ARR10, and ARR12 negatively regulate plant responses to drought. Proc. Natl. Acad. Sci. U.S.A. 113 3090-5 PubMed GONUTS page
↑ Mason, MG et al. (2004) Type-B response regulators display overlapping expression patterns in Arabidopsis. Plant Physiol. 135 927-37 PubMed GONUTS page
↑ Riechmann, JL et al. (2000) Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290 2105-10 PubMed GONUTS page
↑ ^8.0 ^8.1 Hwang, I et al. (2002) Two-component signal transduction pathways in Arabidopsis. Plant Physiol. 129 500-15 PubMed GONUTS page

[PMID:23482873-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Hill, K et al. (2013) Functional characterization of type-B response regulators in the Arabidopsis cytokinin response. Plant Physiol. 162 212-24 PubMed GONUTS page

[PMID:18723577-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Argyros, RD et al. (2008) Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development. Plant Cell 20 2102-16 PubMed GONUTS page

[PMID:28576846-3] Meng, WJ et al. (2017) Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of . Plant Cell 29 1357-1372 PubMed GONUTS page

[PMID:16227453-4] Mason, MG et al. (2005) Multiple type-B response regulators mediate cytokinin signal transduction in Arabidopsis. Plant Cell 17 3007-18 PubMed GONUTS page

[PMID:26884175-5] 5.0 ^5.1 Nguyen, KH et al. (2016) Arabidopsis type B cytokinin response regulators ARR1, ARR10, and ARR12 negatively regulate plant responses to drought. Proc. Natl. Acad. Sci. U.S.A. 113 3090-5 PubMed GONUTS page

[PMID:15173562-6] Mason, MG et al. (2004) Type-B response regulators display overlapping expression patterns in Arabidopsis. Plant Physiol. 135 927-37 PubMed GONUTS page

[PMID:11118137-7] Riechmann, JL et al. (2000) Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290 2105-10 PubMed GONUTS page

[PMID:12068096-8] 8.0 ^8.1 Hwang, I et al. (2002) Two-component signal transduction pathways in Arabidopsis. Plant Physiol. 129 500-15 PubMed GONUTS page

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ARATH:ARR12

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