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ADVG:NS2

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Species (Taxon ID) Aleutian mink disease parvovirus (strain G) (ADV). (10783)
Gene Name(s) No Information Provided.
Protein Name(s) Non-structural protein NS2
External Links
UniProt Q84361
EMBL M20036
JN040434
PIR D36760
RefSeq NP_042873.1
GeneID 1494589
KEGG vg:1494589
Proteomes UP000008470
GO GO:0042025
InterPro IPR020960
Pfam PF12475

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0039693

viral DNA genome replication

PMID:24606679[1]

ECO:0000315

P

Figure 5 and Figure 6 show that Non-structural protein NS2, or just NS2, is involved in viral genome replication. In the presence of the mutant, pIAMDV(-NS2), the aleutian mink disease parvovirus (strain G) (ADV or AMDV) is unable to replicate its genome within the host cell nucleus. In this experiment, they infected CrFK cells (Crandall feline kidney cell) with the aleutian mink disease parvovirus (AMDV-G) to determine the involvement of NS2 in viral genome replication.

complete
CACAO 13459

GO:0019034

viral replication complex

PMID:24606679[1]

ECO:0000314

C

Figure 4 tells us that Non-Structural Protein NS2, or just NS2, from the aleutian mink disease parvovirus (strain G) (ADV or AMDV) is localized inside the viral DNA replication center of the CrFK host cells (Crandall feline kidney cell).

complete
CACAO 13486

part_of

GO:0042025

host cell nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1048
UniProtKB-SubCell:SL-0414

C

Seeded From UniProt

complete

Notes

References

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  1. 1.0 1.1 Huang, Q et al. (2014) Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection. Virology 452-453 23-31 PubMed GONUTS page