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9VIRU:A0A2D0TCG7

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Species (Taxon ID) unidentified phage. (38018)
Gene Name(s) No Information Provided.
Protein Name(s) phage anti-CRISPR AcrIIA4 (ECO:0000313 with PDB:5VZL)
External Links
UniProt A0A2D0TCG7
PDB 5VZL
SMR A0A2D0TCG7

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0098672

evasion by virus of CRISPR-cas system

PMID:30046034[1]

ECO:0000314

P

Fig. 5 demonstrates that acrIIA4 from Listeria monocytogenes prophage is capable of inhibiting the effects of CRISPR-stCas9, but not the effects of spCas9 on sgRNA. Experiment was run on human cells which contained plasmid modifications.

complete
CACAO 13387

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Hynes, AP et al. (2018) Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins. Nat Commun 9 2919 PubMed GONUTS page