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9TRYP:Q8T8E9

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Species (Taxon ID) Trypanosoma brucei. (5691)
Gene Name(s) galE (ECO:0000313 with EMBL:CAD23117.1)
Protein Name(s) UDP-galactose 4-epimerase (ECO:0000313 with EMBL:CAD23117.1)
External Links
UniProt Q8T8E9
EMBL AJ430490
PDB 1GY8
2CNB
PDBsum 1GY8
2CNB
ProteinModelPortal Q8T8E9
SMR Q8T8E9
BindingDB Q8T8E9
ChEMBL CHEMBL1169595
EvolutionaryTrace Q8T8E9
GO GO:0050662
GO:0000166
GO:0003978
GO:0006012
Gene3D 3.40.50.720
InterPro IPR025308
IPR001509
IPR005886
IPR016040
PANTHER PTHR10366:SF186
Pfam PF01370
PF13950
TIGRFAMs TIGR01179

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0020015

glycosome

PMID:24792668[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003978

UDP-glucose 4-epimerase activity

PMID:11983889[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001509

F

Seeded From UniProt

complete

enables

GO:0003978

UDP-glucose 4-epimerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005886

F

Seeded From UniProt

complete

involved_in

GO:0006012

galactose metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005886

P

Seeded From UniProt

complete

enables

GO:0050662

coenzyme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001509

F

Seeded From UniProt

complete

enables

GO:0003978

UDP-glucose 4-epimerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.1.3.2

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Güther, ML et al. (2014) High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics. J. Proteome Res. 13 2796-806 PubMed GONUTS page
  2. Roper, JR et al. (2002) Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei. Proc. Natl. Acad. Sci. U.S.A. 99 5884-9 PubMed GONUTS page