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9STRA:V5RGX6
Contents
Species (Taxon ID) | Nannochloropsis gaditana. (72520) | |
Gene Name(s) | AUREO1 (ECO:0000313 with EMBL:AHB33796.1) | |
Protein Name(s) | Aureochrome 1 (ECO:0000313 with EMBL:AHB33796.1) | |
External Links | ||
UniProt | V5RGX6 | |
EMBL | KF575177 | |
GO | GO:0000155 GO:0043565 GO:0003700 | |
InterPro | IPR004827 IPR001610 IPR000014 IPR000700 | |
Pfam | PF07716 PF13426 | |
SMART | SM00338 SM00086 SM00091 | |
SUPFAM | SSF55785 | |
TIGRFAMs | TIGR00229 | |
PROSITE | PS50217 PS50113 PS50112 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0045723 |
positive regulation of fatty acid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
GO:0045723 |
positive regulation of fatty acid biosynthetic process |
ECO:0000315 |
P |
Figure 2C shows that when cloned into S. cerevisiae, the protein AUREO1 from N. gaditana significantly increased the amount of lipids in the cell compared to the empty vector. Figure 2D shows that the S. cerevisiae mutant expressing the gene has increased expression of ACC1 and DGAT and decreased expression of LACS, genes that increase and decrease fatty acid production respectively, indicating that the increased lipid contents were due to this regulation. The empty vector did not affect expression of the fatty acid synthesis genes. |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Huang, YJ et al. (2014) Overexpression of NgAUREO1, the gene coding for aurechrome 1 from Nannochloropsis gaditana, into Saccharomyces cerevisiae leads to a 1.6-fold increase in lipid accumulation. Biotechnol. Lett. 36 575-9 PubMed GONUTS page