GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

9STRA:V5RGX6

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Nannochloropsis gaditana. (72520)
Gene Name(s) AUREO1 (ECO:0000313 with EMBL:AHB33796.1)
Protein Name(s) Aureochrome 1 (ECO:0000313 with EMBL:AHB33796.1)
External Links
UniProt V5RGX6
EMBL KF575177
GO GO:0000155
GO:0043565
GO:0003700
InterPro IPR004827
IPR001610
IPR000014
IPR000700
Pfam PF07716
PF13426
SMART SM00338
SM00086
SM00091
SUPFAM SSF55785
TIGRFAMs TIGR00229
PROSITE PS50217
PS50113
PS50112

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045723

positive regulation of fatty acid biosynthetic process

PMID:24162136[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004827

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004827

P

Seeded From UniProt

complete

GO:0045723

positive regulation of fatty acid biosynthetic process

PMID:24162136[1]

ECO:0000315

P

Figure 2C shows that when cloned into S. cerevisiae, the protein AUREO1 from N. gaditana significantly increased the amount of lipids in the cell compared to the empty vector.

Figure 2D shows that the S. cerevisiae mutant expressing the gene has increased expression of ACC1 and DGAT and decreased expression of LACS, genes that increase and decrease fatty acid production respectively, indicating that the increased lipid contents were due to this regulation. The empty vector did not affect expression of the fatty acid synthesis genes.

complete
CACAO 9812

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Huang, YJ et al. (2014) Overexpression of NgAUREO1, the gene coding for aurechrome 1 from Nannochloropsis gaditana, into Saccharomyces cerevisiae leads to a 1.6-fold increase in lipid accumulation. Biotechnol. Lett. 36 575-9 PubMed GONUTS page