9CAUD:Q9G097

Species (Taxon ID)	Lactococcus phage TP901-1. (35345)
Gene Name(s)	tmp (ECO:0000313 with EMBL:AAK38062.1)
Protein Name(s)	TMP (ECO:0000313 with EMBL:AAK38062.1) Tape measure protein (ECO:0000313 with EMBL:AAG32164.1)
External Links
UniProt	Q9G097
EMBL	AF252967 AF304433
RefSeq	NP_112708.1
GeneID	921037
KEGG	vg:921037
GO	GO:0016021
InterPro	IPR010090
Pfam	PF10145
TIGRFAMs	TIGR01760

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0098004	virus tail fiber assembly	PMID:27824135	ECO:0000315	mutant phenotype evidence used in manual assertion		P		56 mutants were created to characterize which domains of TP901-1's tape measure gene (TMP) were essential for infection of the phage and it's tail assembly. Through this experiment, TP901-1's N-terminal 154 amino acid residues, C-terminal 60 residues, and hydrophobic region were revealed to be required for TP901's infectivity. This is shown in fig.2 in the paper, where removing 30 amino acids from both N and C-termini cause phage assembly to be aberrant, while removal of the hydrophobic region causes tai length reduction.	complete CACAO 12553
	GO:0098026	virus tail, tube	PMID:27824135	ECO:0000315			C		A series of different mutations were made in the TMP of this phage, including in the N-termini, C-termini, and hydrophobic regions of the protein. Figure 2 shows that mutations in the N and C-termini resulted in abnormal phage assembly, and hydrophobic region mutations resulted in tail length reduction. Therefore, the TMP is determined to be an important part of the tube in the viral tail.	complete CACAO 12588
Contributes to	GO:0098003	viral tail assembly	PMID:27824135	ECO:0000315			P		The 29 repeats of the tape measure protein are essential to virion structure. Deletion mutants for repeat copies were constructed, then had tail length measured through electron microscopy. Authors found that, with increased deletion of repeat sequences, the phage tail shortened (Table 2). For example, normal phage tail length is 118nm, but repeat 1-29 deletion mutants had a tail of 65 nm.	complete CACAO 13108
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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References

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