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9CAUD:H2D0G4

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Species (Taxon ID) Salmonella phage SPN1S. (1125653)
Gene Name(s) No Information Provided.
Protein Name(s) Endolysin (ECO:0000313 with EMBL:AEX26904.1)
External Links
UniProt H2D0G4
EMBL JN391180
RefSeq YP_005098003.1
PDB 4OK7
PDBsum 4OK7
SMR H2D0G4
GeneID 11604964
KEGG vg:11604964
KO K03791
Proteomes UP000008488
GO GO:0004568
GO:0016998
GO:0006032
InterPro IPR000726
IPR023346
Pfam PF00182
SUPFAM SSF53955

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016787

hydrolase activity

PMID:22289622[1]

ECO:0000314

F

In one of the experiments described, they performed an endolysin assay to test the antimicrobial spectrum of this protein. Table 2 displays the relative lysis activity of SPN1S against certain Gram-positive and Gram-negative bacterial strains. The table shows SPN1S's high relative lysis activity against all the E.coli strains. These results provide evidence that the SPN1S protein has a hydrolase function.

complete
CACAO 12590

GO:0009253

peptidoglycan catabolic process

PMID:22289622[1]

ECO:0000314

P

Figure 5 shows a line (A) and histogram(B) that plots the peptidoglycan degradation in Ecoli in response to the introduction of SPN1S endolysin into the sample. The endolysin seems to cleave the glycosydic linkage between the peptidoglycan molecules to reduce the overall optical density.

complete
CACAO 12601

enables

GO:0004568

chitinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000726

F

Seeded From UniProt

complete

involved_in

GO:0006032

chitin catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000726

P

Seeded From UniProt

complete

involved_in

GO:0016998

cell wall macromolecule catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000726

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Lim, JA et al. (2012) Characterization of endolysin from a Salmonella Typhimurium-infecting bacteriophage SPN1S. Res. Microbiol. 163 233-41 PubMed GONUTS page