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9CAUD:D6QY02

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Species (Taxon ID) Staphylococcus phage GH15. (760530)
Gene Name(s) lysGH15 (ECO:0000313 with EMBL:ADG26756.1)
Protein Name(s) Endolysin (ECO:0000313 with EMBL:ADG26756.1)

Putative lysin (ECO:0000313 with EMBL:AFF28543.1)

External Links
UniProt D6QY02
EMBL HM015284
JQ686190
RefSeq YP_007002194.1
PDB 2MK5
4OLK
4OLS
PDBsum 2MK5
4OLK
4OLS
GeneID 14005855
GO GO:0046872
GO:0008745
GO:0009253
Gene3D 3.40.80.10
InterPro IPR002502
IPR007921
IPR003646
Pfam PF01510
PF05257
PF08460
SMART SM00644
SM00287
SUPFAM SSF55846
PROSITE PS50911

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044659

cytolysis by virus of host cell

PMID:21048011[1]

ECO:0000314

P

Figure 5 shows Lysgh15 induced lysis in various staphylococcus strains.

complete
CACAO 10741

involved_in

GO:0044659

cytolysis by virus of host cell

PMID:21048011[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008745

N-acetylmuramoyl-L-alanine amidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002502
InterPro:IPR036505

F

Seeded From UniProt

complete

involved_in

GO:0009253

peptidoglycan catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002502
InterPro:IPR036505

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gu, J et al. (2011) LysGH15, a novel bacteriophage lysin, protects a murine bacteremia model efficiently against lethal methicillin-resistant Staphylococcus aureus infection. J. Clin. Microbiol. 49 111-7 PubMed GONUTS page