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9CAUD:A0A220GHA5
Contents
| Species (Taxon ID) | Streptococcus phage D4276. (2006928) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | AcrIIA5 (ECO:0000313 with EMBL:ASD50988.1) | |
| External Links | ||
| UniProt | A0A220GHA5 | |
| EMBL | MF161328 | |
| Proteomes | UP000224125 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0098672 |
evasion by virus of CRISPR-cas system |
ECO:0000314 |
P |
Fig. 5 demonstrates that acrIIA5 is capable of inhibiting the effects of CRISPR-stCas9 and spCas9 on sgRNA. Experiment was run on human cells which contained plasmid modifications. |
complete | |||||
| GO:0098672 |
evasion by virus of CRISPR-cas system |
ECO:0007040 |
P |
Figure 2b shows how the activity of an Anti-CRISPR protein (acrIIA5) with A CR1 immune cell in a Streptococcus phage (D4276) can increase sensitivity to cos-type phage D5842 |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Hynes, AP et al. (2018) Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins. Nat Commun 9 2919 PubMed GONUTS page
- ↑ Hynes, AP et al. (2017) An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9. Nat Microbiol 2 1374-1380 PubMed GONUTS page
