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dictyBase:pkar

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Species (Taxon ID) Dictyostelium discoideum (taxon:44689)
Gene Name(s) pkar ( synonyms: PKA, rdeC, cAK )
Protein Name(s) protein kinase A regulatory subunit,
External Links
dictyBase DDB_G0279413

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0004190

aspartic-type endopeptidase activity

dictyBase_REF:11553

IEA: Inferred from Electronic Annotation

InterPro:IPR001969

F

Seeded from UniProt.

GO:0005764

lysosome

dictyBase_REF:2541
PMID:11854420[1]

IDA: Inferred from Direct Assay

C

Seeded from UniProt.

GO:0006508

proteolysis

dictyBase_REF:11553

IEA: Inferred from Electronic Annotation

InterPro:IPR001461

P

Seeded from UniProt.

GO:0005813

centrosome

dictyBase_REF:10187
PMID:15548420[2]

TAS: Traceable Author Statement

C

From dictyBase

GO:0005829

cytosol

dictyBase_REF:10170
PMID:15473840[3]

TAS: Traceable Author Statement

C

From dictyBase

GO:0005952

cAMP-dependent protein kinase complex

dictyBase_REF:11553

IEA: Inferred from Electronic Annotation

InterPro:IPR002373

C

From dictyBase

GO:0008603

cAMP-dependent protein kinase regulator activity

dictyBase_REF:5755
PMID:1312226[4]

IMP: Inferred from Mutant Phenotype

F

From dictyBase

GO:0016301

kinase activity

dictyBase_REF:11554

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

From dictyBase

GO:0030435

sporulation resulting in formation of a cellular spore

dictyBase_REF:9833
PMID:14695060[5]

IMP: Inferred from Mutant Phenotype

P

From dictyBase

GO:0030552

cAMP binding

dictyBase_REF:5755
PMID:1312226[4]

IMP: Inferred from Mutant Phenotype

F

From dictyBase

GO:0030817

regulation of cAMP biosynthetic process

dictyBase_REF:5755
PMID:1312226[4]

IMP: Inferred from Mutant Phenotype

P

From dictyBase

GO:0030819

positive regulation of cAMP biosynthetic process

dictyBase_REF:9955
PMID:15131307[6]

IDA: Inferred from Direct Assay

P

From dictyBase

GO:0031285

regulation of sorocarp stalk cell differentiation

dictyBase_REF:8190
PMID:12455979[7]

IGI: Inferred from Genetic Interaction

dictyBase:DDB0191260

P

From dictyBase


Notes

References

See Help:References for how to manage references in GONUTS.

  1. Harris, E et al. (2002) Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome. Mol. Biol. Cell 13 656-69 PubMed GONUTS page
  2. Gräf, R et al. (2004) Molecular and functional analysis of the dictyostelium centrosome. Int. Rev. Cytol. 241 155-202 PubMed GONUTS page
  3. Manahan, CL et al. (2004) Chemoattractant signaling in dictyostelium discoideum. Annu. Rev. Cell Dev. Biol. 20 223-53 PubMed GONUTS page
  4. 4.0 4.1 4.2 Simon, MN et al. (1992) Mutation of protein kinase A causes heterochronic development of Dictyostelium. Nature 356 171-2 PubMed GONUTS page
  5. Steinert, M et al. (2003) Surrogate hosts: protozoa and invertebrates as models for studying pathogen-host interactions. Int. J. Med. Microbiol. 293 321-32 PubMed GONUTS page
  6. Maeda, M et al. (2004) Periodic signaling controlled by an oscillatory circuit that includes protein kinases ERK2 and PKA. Science 304 875-8 PubMed GONUTS page
  7. Wang, B & Kuspa, A (2002) CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp. Eukaryotic Cell 1 126-36 PubMed GONUTS page


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