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YERPU:A0A0N9NCU6
Contents
| Species (Taxon ID) | Yersinia pseudotuberculosis. (633) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Effector protein YopJ (ECO:0000313 with EMBL:ALG88417.1)
Type III secretion system effector acetyltransferase YopJ (ECO:0000313 with EMBL:AYW89929.1) | |
| External Links | ||
| UniProt | A0A0N9NCU6 | |
| EMBL | KT307967 CP033712 CP033714 | |
| RefSeq | WP_002225474.1 | |
| ProteinModelPortal | A0A0N9NCU6 | |
| SMR | A0A0N9NCU6 | |
| OrthoDB | 1119222at2 | |
| Proteomes | UP000268669 UP000277634 | |
| InterPro | IPR005083 | |
| Pfam | PF03421 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0016740 |
transferase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
||||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
||||
| GO:1903753 |
negative regulation of p38MAPK cascade |
ECO:0000279 |
P |
occurs_in:CL:0000235 |
CL:0000235 occurs in human macrophages. Figure 6 shows J774A.1 macrophages infected with Yersinia pseudotuberculosis strains both able and unable to secrete full-length translocon YopJ for 1 hour, and protein samples were taken to be analyzed by immunoblotting with anti-P38, indicating down-regulation of P38 by YopJ. Yersinia pseudotuberculosis |
complete | ||||
| GO:0046329 |
negative regulation of JNK cascade |
ECO:0000279 |
P |
occurs_in:CL:0000235 |
CL:0000235 occurs in human macrophages. Figure 6c shows J774A.1 macrophages were infected with Yersinia pseudotuberculosis strains both able and unable to secrete full-length translocon YopJ for 1 hour. Cell lysates were taken for immunoblotting with a phosphospecific anti-JNK antibody. Blotting showed YopJ down regulated JNK in macrophages. Yersinia pseudotuberculosis |
complete | ||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Palmer, LE et al. (1998) YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol. Microbiol. 27 953-65 PubMed GONUTS page
