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YERPS:YOPJ
Contents
| Species (Taxon ID) | Yersinia pseudotuberculosis serotype I (strain IP32953). (273123) | |
| Gene Name(s) | yopJ | |
| Protein Name(s) | Effector protein YopJ
Virulence factor YopJ | |
| External Links | ||
| UniProt | P31498 | |
| EMBL | L33833 AY606230 BX936399 M58506 | |
| RefSeq | YP_009079298.1 YP_068507.1 | |
| ProteinModelPortal | P31498 | |
| STRING | 273123.pYV0098 | |
| MEROPS | C55.001 | |
| EnsemblBacteria | CAF25441 | |
| GeneID | 2952991 | |
| KEGG | yps:pYV0098 | |
| PATRIC | 18637948 | |
| eggNOG | NOG114820 | |
| HOGENOM | HOG000219637 | |
| KO | K08598 | |
| OMA | RLNEYVQ | |
| OrthoDB | EOG6D8B7D | |
| BioCyc | YPSE273123:GI1M-4194-MONOMER | |
| Proteomes | UP000001011 | |
| GO | GO:0005576 GO:0016746 GO:0009405 | |
| InterPro | IPR005083 | |
| Pfam | PF03421 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0042536 |
negative regulation of tumor necrosis factor biosynthetic process |
ECO:0000335 |
substance quantification evidence |
P |
occurs_in:CL:0000235 |
Figure 3b shows that strain YP25, defective for secretion of effector YopJ, had increased macrophage TNF-alpha production after J774A.1 macrophages were infected with Yersinia pseudotuberculosis strains both able and unable to secrete YopJ. Yersinia pseudotuberculosis accuring in human macrophages. |
complete | |||
|
enables |
GO:0016746 |
transferase activity, transferring acyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Palmer, LE et al. (1998) YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol. Microbiol. 27 953-65 PubMed GONUTS page
b
