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YERPE:O68704
Contents
| Species (Taxon ID) | Yersinia pestis. (632) | |
| Gene Name(s) | yopK (ECO:0000313 with EMBL:AAC62583.1) (synonyms: yopQ (ECO:0000313 with EMBL:AAC62583.1)) | |
| Protein Name(s) | Putative virulence determinant protein (ECO:0000313 with EMBL:CAB54896.1)
Type III secretion negative modulator of injection (ECO:0000313 with EMBL:ADV16687.1) Yop targeting protein (ECO:0000313 with EMBL:AAC69810.1) YopK (YopQ) homolog (ECO:0000313 with EMBL:AAC62583.1) | |
| External Links | ||
| UniProt | O68704 | |
| EMBL | AF053946 AF074612 HQ612242 AL117189 QANK01000218 | |
| PIR | T43602 | |
| RefSeq | NP_395154.1 NP_857759.1 NP_857959.1 WP_002213007.1 | |
| IntAct | O68704 | |
| DNASU | 1149323 | |
| GeneID | 1149323 1172664 15151812 | |
| KEGG | ype:YPCD1.19c ypj:CH55_4314 ypl:CH46_4419 ypv:BZ15_4375 ypw:CH59_4462 | |
| PATRIC | fig|214092.21.peg.23 | |
| HOGENOM | HOG000219594 | |
| Proteomes | UP000000815 | |
| InterPro | IPR016505 | |
| PIRSF | PIRSF007043 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0005515 |
protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
||||
| GO:1900226 |
negative regulation of NLRP3 inflammasome complex assembly |
ECO:0005581 |
enzyme-linked immunoabsorbent assay evidence used in manual assertion |
P |
Figure 3E,G YopK mutants showed a sharp increase in IL-1B production in 3E. 3G shows the independence of this effect on Pyrin, but its dependence on NLRP3/NLRC4 pathway. Yersinia pestis |
complete | ||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yang, H et al. (2011) Insight into bacterial virulence mechanisms against host immune response via the Yersinia pestis-human protein-protein interaction network. Infect. Immun. 79 4413-24 PubMed GONUTS page
- ↑ Ratner, D et al. (2016) The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation. PLoS Pathog. 12 e1006035 PubMed GONUTS page
