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YERPE:A0A3N4BLC7

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Species (Taxon ID) Yersinia pestis. (632)
Gene Name(s) rfaL (ECO:0000313 with EMBL:AAS63912.1)
Protein Name(s) O-antigen ligase family protein (ECO:0000313 with EMBL:ROZ90153.1)

Putative O-antigen biosynthesis protein (ECO:0000313 with EMBL:AAS63912.1)

External Links
UniProt A0A3N4BLC7
EMBL AE009952
AE017042
RKJO01000004
UHIZ01000001
PIR AH0051
RefSeq WP_002209197.1
DNASU 1148709
KEGG ypk:y3762
ypl:CH46_497
ypm:YP_3764
ypv:BZ15_3154
ypw:CH59_1444
eggNOG ENOG4105UG0
COG3307
HOGENOM HOG000219167
Proteomes UP000001019
UP000002490
UP000254656
UP000277015
GO GO:0016021
GO:0016874

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0016874

ligase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

enables

GO:0016874

ligase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

GO:0030254

protein secretion by the type III secretion system

PMID:23357388[1]

ECO:0007122

P

Figure S1A shows the dependence on RfaL in the presence of calcium for secretion of late-phase type III secretion system proteins in Yersinia pestis through secretion assays followed by western blotting using anti YopD (early T3SS protein) and YopE (late T3SS protein) in WT, RfaL mutant, and RfaL complemented strains. YopD is still secreted in RfaL mutant in the absence of calcium, but to a lesser extent.

submitted a new term request for an evidence code describing secretion assays - waiting on term.

complete
CACAO 13726

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Houppert, AS et al. (2013) RfaL is required for Yersinia pestis type III secretion and virulence. Infect. Immun. 81 1186-97 PubMed GONUTS page